Results 111 to 120 of about 8,166 (301)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Open/Closed BPS Correspondence and Integrality

open access: yes
We prove the integrality and finiteness of open BPS invariants of toric Calabi-Yau 3-folds relative to Aganagic-Vafa outer branes, defined from open Gromov-Witten invariants by the Labastida-Mariño-Ooguri-Vafa formula. Specializing to disk invariants, we
Yu, Song
core   +1 more source

Improving Modular Bootstrap Bounds with Integrality

open access: yes, 2023
We implement methods that efficiently impose integrality -- i.e., the condition that the coefficients of characters in the partition function must be integers -- into numerical modular bootstrap.
Li, Wei, Fitzpatrick, A. Liam
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Humanization as an expression of Integrality

open access: yesO Mundo da Saúde, 2012
The article opens with the discussion of the amplitude of the senses of integrality in conceptual terms. In the sequence, humanization is characterized in the way defined in contemporary literature.
Inajara Carla Oliveira   +1 more
doaj  

Prediction model of no-response before the first transarterial chemoembolization for hepatocellular carcinoma: TACF score. [PDF]

open access: yesDiscov Oncol, 2023
Zhong JW   +10 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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