HIV Dynamics and Integrase Inhibitors
The integrase inhibitor (INI) raltegravir has shown promising results in clinical trials to date, reducing second phase HIV RNA levels by 70% in comparison with standard regimens. These trial results have been limited by the 50 copies/ml detection limit of the HIV RNA assay and have not investigated the effect of an INI regimen on levels of latently ...
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Long-term transgene expression in mouse neural progenitor cells modified with ϕC31 integrase
Annahita Keravala +3 more
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Biochemical characteristics of functional domains using feline foamy virus integrase mutants [PDF]
Gwi-Woong Yoo, Cha-Gyun Shin
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Integrase strand-transfer inhibitor polymorphic and accessory resistance substitutions in patients with acute/recent HIV infection—authors’ response [PDF]
Juan Ambrosioni +2 more
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Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase [PDF]
Peter K. Quashie +8 more
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Processing of viral DNA by retroviral integrase leaves a dinucleotide single-strand overhang in the unprocessed strand. Previous studies have stressed the importance of the 5' single-stranded (ss) tail in the integration process.
JORGE VERA +3 more
doaj
Integrase-mediated differentiation circuits improve evolutionary stability of burdensome and toxic functions in E. coli [PDF]
Rory L. Williams, Richard M. Murray
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Viruses Previously Classified as CRF146_BC, a Circulating Recombinant Form of HIV-1 Recently Reported in Brazil, Represent Different Recombinant Forms, One of Which Is Circulating in Spain. [PDF]
Donoso A +17 more
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