Results 121 to 130 of about 52,284 (201)

First Report of blaCTX‐M‐15 in a Marine Thermotolerant Enterobacter Isolate From Bangladesh: Genomic Insights Into Halotolerance and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Marine‐derived Enterobacter kobei, exhibiting thermotolerance and salt tolerance, is ESBL‐producing and harbors AMR genes (blaCTX‐M‐15, qnrS1) and mobile genetic elements, indicating environmental spread of antimicrobial resistance. ABSTRACT Marine ecosystems are becoming important reservoirs for antimicrobial resistance (AMR). However, genomic data on
Md. Arifur Rahman, Rafid Muntasir Ul Azam, Md. Sazib Hossain, Samina Momtaz, Anowara Begum, Munawar Sultana   +5 more
wiley   +1 more source

Population Pharmacokinetics of Dolutegravir in Plasma and Cerebrospinal Fluid in Adults Living With HIV

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 10, October 2026.
ABSTRACT Characterizing dolutegravir penetration into the central nervous system is important for optimizing human immunodeficiency virus treatment outcomes, yet population‐specific pharmacokinetic data describing cerebrospinal fluid disposition and equilibration kinetics remain lacking.
Mohammed W. Ali, Sam Nightingale, Tracy Kellermann, John Joska, Alan Winston, Saye Khoo, Joseph F. Standing, Eric H. Decloedt, Ahmed A. Abulfathi   +8 more
wiley   +1 more source

The mutational analysis of C31 integrase

, 2007
The integrase protein from the bacteriophage ~C31 is a member of the large serine recombinase family. Purified ~C31 integrase has been shown to only catalyse site-specific recombination between the DNA sites attB and attP in vitro.
Rowley, Paul Andrew
core  

Identification of Molecular Pathways Underlying Mn(II) Oxidation in Pseudomonas resinovorans

Environmental Microbiology, Volume 28, Issue 10, October 2026.
Transposon mutagenesis in biofilter‐associated Pseudomonas resinovorans MOB‐513 identifies a c‐di‐GMP‐dependent regulatory network involving type IV pili, two‐component systems, and diguanylate cyclases that controls Mn(II) oxidation and biofilm formation, providing new insight into microbial manganese cycling and biofilter performance.
Ainelén Piazza, Lucia Parra, Marilina Gaffuri, Jacob G. Malone, Jorgelina Ottado, Natalia Gottig   +5 more
wiley   +1 more source

Genomic and Phenotypic Classification of Staphylococcus Species Isolated From Delhi Air

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Multiple Staphylococcus spp. were isolated from the outdoor polluted air of the Indian Capital, New Delhi. The bacterial samples were collected from 6 different locations, and the whole genome of four Staphylococcus isolates was sequenced in their entirety. This study presents the comparative genomic analysis of these four isolates.
Himanshu Sen, Joyasree Das, Suman Paul, Manpreet Kaur, Amareshwar Vodapalli, Surajit Bhattacharjee, Manoj Raje, Srinivasan Krishnamurthi, Saumya Raychaudhuri   +8 more
wiley   +1 more source

A Bacillus Phage From Bangladeshi Soil, Phage APU1: Genomic Characterisation and Comparative Genomic Analysis

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Phage APU1, isolated from Bangladeshi agricultural soil, is a high‐quality, computationally predicted lytic Bacillus phage with a 153,847‐bp genome and no detected antimicrobial resistance or virulence factor genes. Comparative genomics identified APU1 as a genomically distinct member of a related Bacillus phage group.
Arefeen Haider, Tasnuva Jahan Esha, Sezanur Rahman, Jannat Akther, Naimul Islam Faysal, Tahsin Khan, Shakhinur Islam Mondal, Anowara Begum, Sudhangshu Kumar Biswas, Mustafizur Rahman, Mohammad Jubair   +10 more
wiley   +1 more source

Thymic Involution and Function in People With HIV and General Population Controls: A Cross‐Sectional Analysis From Two Danish Cohort Studies

Aging Cell, Volume 25, Issue 10, October 2026.
Thymic involution, the age‐related replacement of thymic soft tissue by fat, has been linked to immunosenescence and chronic inflammation. Whether HIV infection affects thymic involution remains unclear. We found that people with HIV on long‐term antiretroviral therapy had more thymic tissue than controls, indicating less thymic involution. More thymic
Manon C. Vanbellinghen, Anders Boyd, Andreas Ohrt Johansen, Moises Alberto Suarez‐Zdunek, Andreas Dehlbæk Knudsen, Thomas Skårup Kristensen, Jørgen Tobias Kühl, Per Ejlstrup Sigvardsen, Michael Huy Cuong Pham, Andreas Fuchs Larsen, Klaus Fuglsang Kofoed, Børge Grønne Nordestgaard, Shoaib Afzal, Neeltje Kootstra, Susanne Dam Nielsen, Peter Reiss   +15 more
wiley   +1 more source

SIEDY Diagnostic Accuracy in Assessing Erectile Dysfunction in Young Men Living With HIV

Andrology, Volume 14, Issue 7, Page 2290-2296, October 2026.
ABSTRACT Background Erectile dysfunction (ED) is a multidimensional condition commonly affecting men living with HIV. The structured interview of erectile dysfunction (SIEDY) is the only validated tool assessing organic, relational, and psychological factors contributing to ED, while dynamic penile color Doppler ultrasound (dPCDU) is a reliable method ...
Giorgio Tiecco, Federico Cesanelli, Cosimo Colangelo, Marco Di Gregorio, Andrea Delbarba, Paolo Facondo, Matteo Riva, Carlo Cappelli, Emanuele Focà, Francesco Castelli, Eugenia Quiros‐Roldan   +10 more
wiley   +1 more source

Characterization and structural analysis of HIV-1 integrase conservation

, 2009
The HIV-1 integrase, responsible for the chromosomal integration of the newly synthesized double-stranded viral DNA into the host genomic DNA, represents a new and important target of potential clinical relevance.
Perno, CF, Marcelin, AG, PERNO, CARLO FEDERICO, Antinori, A, Malet, I, D'Arrigo, R, CECCHERINI SILBERSTEIN, FRANCESCA, Ceccherini-Silberstein, F   +7 more
core   +1 more source

Characterization of the long-terminal repeat single-strand tail-binding site of Moloney-MuLV integrase by crosslinking

Biological Research, 2008
Processing of viral DNA by retroviral integrase leaves a dinucleotide single-strand overhang in the unprocessed strand. Previous studies have stressed the importance of the 5' single-stranded (ss) tail in the integration process.
JORGE VERA, BEATRIZ VALENZUELA, MÓNICA J ROTH, ÓSCAR LEÓN   +3 more
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