Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno +13 more
wiley +1 more source
Semaglutide improves MASLD and MASH in people with HIV: The SLIM LIVER study
Abstract Objectives We have shown that semaglutide, a glucagon‐like peptide‐1 receptor agonist (GLP‐1RA), is a highly effective therapy for metabolic dysfunction‐associated steatotic liver disease (MASLD) in people with HIV (PWH). The OWLiver® metabolomics algorithms allow non‐invasive MASLD severity staging without liver biopsy, but the use of ...
Jordan E. Lake +9 more
wiley +1 more source
Abstract Objectives Low‐level viraemia (LLV) persists in some people living with HIV despite antiretroviral therapy, raising concerns about virologic failure. We assessed the characteristics, management and outcomes of LLV in Greece, where next‐generation sequencing, therapeutic drug monitoring and electronic adherence monitoring are unavailable ...
Lydia Leonidou +13 more
wiley +1 more source
Abstract Objectives Frailty is relevant to HIV care across middle and later life, yet Japanese data remain limited. We evaluated frailty, prefrailty and associated factors in Japanese people with HIV using the revised Japanese Cardiovascular Health Study (J‐CHS) criteria.
Hideta Nakamura +15 more
wiley +1 more source
HIV-1 integrase inhibitor resistance in viraemic-treated individuals and baseline capsid diversity relevant to future lenacapavir therapy. [PDF]
Abdullahi A +12 more
europepmc +1 more source
In vitro properties of large serine integrase hybrids derived from ϕC31 and TG1 integrases. [PDF]
Lawson-Williams M +4 more
europepmc +1 more source
A structure-function analysis of P2 integrase
Bacteriophage P2 integrase catalyzes site-specific recombination between the phage DNA and the host chromosome thereby promoting integration or excision of the phage genome.
Sylwan, Lina, +4 more
core
Comparative Genomics of the <i>Enterobacter cloacae</i> Mobilome: Prophage Diversity and Anti-Phage Defense Systems in Phage Satellites. [PDF]
Alrafaie A, Alqurainy N.
europepmc +1 more source
Correction: Longitudinal changes in circulating biomarkers from baseline to week 48 in treatment-Naïve people living with HIV initiating integrase inhibitor-based antiretroviral therapy. [PDF]
Blanco JR +17 more
europepmc +1 more source
Seasonal Occurrence, Population Diversity, and Mobilome Features of Environmental <i>Vibrio parahaemolyticus</i> in Coastal and Estuarine Waters of Haiyan, Zhejiang, China. [PDF]
Xu J, He Y, He P.
europepmc +1 more source

