Results 161 to 170 of about 84,131 (280)

Willingness to participate in clinical trials and expectations towards antiretroviral therapy among heavily treatment‐experienced people living with HIV: A feasibility survey

HIV Medicine, Volume 26, Issue 8, Page 1251-1257, August 2025.
Abstract Introduction As life expectancy among persons with HIV on antiretroviral therapy (ART) is increasing, comorbidities and polypharmacy increase. Drug–drug interactions (DDIs) are common among persons with HIV with a history of virological failure, since many are receiving boosted ART.
Marie Ballif, Manuela Correia da Silva Saúde, David Haerry, Marcel Stoeckle, Patrick Schmid, Dominique Braun, Alexandra Calmy, Gilles Wandeler, Bernard Surial   +8 more
wiley   +1 more source

Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type- integrase [PDF]

, 1995
Abhijit Mazumder, Yves Pommier
openalex   +1 more source

Long‐acting injectable cabotegravir and rilpivirine in observational cohort studies: A systematic review on virological failure, resistance and re‐suppression outcomes in virally suppressed individuals living with HIV

HIV Medicine, Volume 26, Issue 8, Page 1267-1288, August 2025.
Abstract Introduction Randomized controlled trial evidence suggests that long‐acting injectable (LA‐I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice evidence is lacking. Integrase inhibitor (INI) resistance may limit future therapy.
Kyle Ring, Alexa Elias, Megan Devonald, Melanie Smuk, Chloe Orkin   +4 more
wiley   +1 more source

Factors mediating and associated with immunological response in women living with HIV in Sweden: A nationwide register‐based study

HIV Medicine, Volume 26, Issue 8, Page 1311-1316, August 2025.
Abstract Introduction Women remain underrepresented in studies on immunological response (IR) among virally suppressed people living with HIV. Despite receiving antiretroviral therapy (ART) some individuals do not attain an IR, increasing their risk of non‐AIDS morbidity and mortality.
Josefin Nilsson, Olof Elvstam, Erik Sörstedt, Philippe Wagner, Piotr Nowak, Johanna Brännström, Christina Carlander   +6 more
wiley   +1 more source

Synthesis and Anti-Human Immunodeficiency Virus Type 1 Integrase Activity of Hydroxybenzoic and Hydroxycinnamic Acid Flavon-3-yl Esters [PDF]

, 1998
Nicoletta Desideri, Isabella Sestili, M. L. STEIN, Enzo Tramontano, Simona Corrias, P. La Colla   +5 more
openalex   +1 more source

Effectiveness of switching to doravirine‐based antiretroviral therapy: A real‐world study in Germany

HIV Medicine, Volume 26, Issue 8, Page 1289-1299, August 2025.
Abstract Objectives Doravirine (DOR)‐based antiretroviral therapy (ART) has been shown in clinical trials to be effective and well tolerated in treating HIV‐1. The EffectiVeness of SwItChing to DORavirine‐based Antiretroviral Therapy (VICDOR) study characterized the use, effectiveness and impact on body weight and lipids of DOR‐based ART in a ...
Christoph Wyen, Michael Sabranski, Celia Jonsson‐Oldenbüttel, Johannes Bogner, Heribert Knechten, Stefan Esser, Nazifa Qurishi, Sven Schellberg, Irina Kolobova, Jann‐Patrick Pelz, Yohance O. Whiteside, Bekana K. Tadese, Jürgen K. Rockstroh   +12 more
wiley   +1 more source

Characterization of the long-terminal repeat single-strand tail-binding site of Moloney-MuLV integrase by crosslinking

Biological Research, 2008
Processing of viral DNA by retroviral integrase leaves a dinucleotide single-strand overhang in the unprocessed strand. Previous studies have stressed the importance of the 5' single-stranded (ss) tail in the integration process.
JORGE VERA, BEATRIZ VALENZUELA, MÓNICA J ROTH, ÓSCAR LEÓN   +3 more
doaj  

Conjugative transposition of Tn916 requires the excisive and integrative activities of the transposon-encoded integrase

, 1991
M J Storrs, Claire Poyart, Patrick Trieu‐Cuot, Patrice Courvalin   +3 more
openalex   +1 more source

The road less taken: Dihydroflavonol 4‐reductase inactivation and delphinidin anthocyanin loss underpins a natural intraspecific flower colour variation

Molecular Ecology, Volume 34, Issue 15, August 2025.
Abstract Visual cues are of critical importance for the attraction of animal pollinators, however, little is known about the molecular mechanisms underpinning intraspecific floral colour variation. Here, we combined comparative spectral analysis, targeted metabolite profiling, multi‐tissue transcriptomics, differential gene expression, sequence ...
Darren C. J. Wong, Zemin Wang, James Perkins, Xin Jin, Grace Emma Marsh, Emma Grace John, Rod Peakall   +6 more
wiley   +1 more source

Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

, 1992
Robert L. LaFemina, Christine L. Schneider, Helen L. Robbins, P L Callahan, K LeGrow, E. Jill Roth, William A. Schleif, Emilio A. Emini   +7 more
openalex   +1 more source