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HIV Integrase Structure and Function
1999HIV integrase consists of three domains, the structures of which have been individually determined by X-ray crystallography or NMR spectroscopy. The core domain, spanning residues 50-212, is responsible for the catalytic activity of the enzyme.
D, Esposito, R, Craigie
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Recent Advances in Small-Molecule HIV-1 Integrase Inhibitors
Current Medicinal Chemistry, 2021Chao Zhang, Qian Xie, Zhe Jin
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Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75
Nucleic Acids Research, 2021Delphine Lapaillerie +2 more
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Integrase inhibitors to treat HIV/Aids
Nature Reviews Drug Discovery, 2005Yves Pommier +2 more
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