Results 81 to 90 of about 633,523 (228)

Human immunodeficiency virus : 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus [PDF]

, 2009
The human immunodeficiency virus (HIV) had spread unrecognized in the human population as sexually transmitted disease and was finally identified by its disease AIDS in 1981.
Hans Wilhelm Doerr, Lutz Gürtler, Gürtler, Lutz, Stürmer, Martin, Doerr, Hans Wilhelm, Martin Stürmer   +5 more
core   +1 more source

Dietary counselling and exercise training for lipid management in people living with HIV: A systematic review and meta‐analysis

HIV Medicine, EarlyView.
Abstract Objectives Dyslipidaemia is highly prevalent among people living with human immunodeficiency virus (HIV) and contributes to increased cardiovascular risk. Although lifestyle interventions are recommended, evidence specific to people living with HIV remains limited. Previous reviews have primarily focused on dietary interventions or low‐density
Maki Aomori, Hitomi Maeda
wiley   +1 more source

Analogue and structure based approaches for modelling HIV-1 integrase inhibitors

, 2023
A set of 220 inhibitors belonging to different structure classes and having HIV-1 integrase activity were collected along with their experimental pIC50 values. Geometries of all the inhibitors were fully optimized using B3LYP/6-31 + G(d) level of theory.
Suresh Kumar (545197), Satish Kumar Rajouria (14563422), Bhavana Panthi (13046374), Shubham Verma (10578103), Anurag Upadhyaya (11336760), Hemant Kumar Srivastava (472960), Pranjal Chandra (2002714)   +6 more
core   +1 more source

Venezuelan migrants living with HIV in Barcelona: Migration patterns and baseline immunovirological characteristics in a retrospective cohort study

HIV Medicine, EarlyView.
Abstract Objectives To describe the sociodemographic characteristics, migration patterns and immunovirological outcomes of Venezuelan migrants living with HIV (PLWH) in Barcelona, Spain, and to compare them with other Latin American (LA) migrant PLWH. Methods We conducted a retrospective observational cohort study including LA migrant PLWH who attended
Alexy Inciarte, Elizabeth Zamora‐Clemente, Leire Berrocal, Ana González‐Cordón, Lorena De La Mora, María Martínez‐Rebollar, Montserrat Laguno, Juan Ambrosioni, Iván Chivite, Elisa de Lazzari, Alberto Foncillas, Júlia Calvo, Abiu Sempere, Esteban Martínez, José M. Miró, José Luis Blanco, Berta Torres, Josep Mallolas   +17 more
wiley   +1 more source

Real‐world use and effectiveness of fostemsavir in a US clinical setting: Insights from Trio Health HIV Research Network

HIV Medicine, EarlyView.
Abstract Objective To describe real‐world patterns of use, virologic and immunologic outcomes and treatment persistence among people with HIV (PWH) initiating fostemsavir (FTR) in a diverse US cohort. Design Retrospective cohort study of adults receiving FTR in clinical practice, stratified by baseline viral suppression status.
Richard Elion, Cassidy Henegar, Isobel McEwen, Andrew Frick, Moti Ramgopal, Steven Santiago, Karam Mounzer, Gregory Huhn, Charles Walworth, Leigh Ragone, Vani Vannappagari   +10 more
wiley   +1 more source

Non-integrase mechanisms for dolutegravir resistance

Retrovirology
Background Antiretroviral inhibitors that target specific aspects of human immunodeficiency virus 1 (HIV-1) replication have made a huge impact on the management of the global AIDS pandemic and the health and well-being of people that live with HIV ...
Alan N. Engelman
doaj   +1 more source

HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence

Molecules, 2018
HIV-1 integrase (IN) inhibitors represent a new class of highly effective anti-AIDS therapeutics. Current FDA-approved IN strand transfer inhibitors (INSTIs) share a common mechanism of action that involves chelation of catalytic divalent metal ions ...
Xue Zhi Zhao, Mathieu Métifiot, Evgeny Kiselev, Jacques J. Kessl, Kasthuraiah Maddali, Christophe Marchand, Mamuka Kvaratskhelia, Yves Pommier, Terrence R. Burke   +8 more
doaj   +1 more source

Stability of the HIV cascade of care throughout the COVID‐19 pandemic in Europe: Results from the multinational EuroSIDA cohort study (2016–2022)

HIV Medicine, EarlyView.
Abstract Background Prior to the COVID‐19 pandemic, antiretroviral therapy (ART) coverage and viral suppression were improving across Europe; however, the impact of the pandemic on HIV care remains uncertain. Methods In‐person visits, ART coverage and viral suppression among those on ART were described in the EuroSIDA cohort for each calendar year from
Olga Fursa, Wendy Bannister, Giovanni Guaraldi, Justyna Kowalska, Jose M. Miro, Robert Zangerle, David Jilich, Jean‐Paul Viard, Katharina Kusejko, Piotr Nowak, Pere Domingo, Claire Mackintosh, Antonella Castagna, Thomas Benfield, Bartosz Szetela, Johannes Bogner, Marta Boffito, Lars Peters, on behalf of the EuroSIDA study group   +18 more
wiley   +1 more source

HIV - recentes avanços na pesquisa de fármacos HIV - highlights in drug research

Química Nova, 2008
The development of new antiretroviral drugs is a dynamic process that is continuously fueled by identification of new molecular targets and new compounds for know targets.
Wilson Cunico, Claudia R. B. Gomes, Walcimar T. Vellasco Junior   +2 more
doaj   +1 more source

HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise

HIV Medicine, EarlyView.
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil, Nicola Wearne, Brendon Price, Frank Post, Dami A. Collier   +4 more
wiley   +1 more source