Results 151 to 160 of about 31,823 (275)
Effect of Pyrolysis on the Removal of Antibiotic Resistance Genes and Class I Integrons from Municipal Wastewater Biosolids [PDF]
Wastewater biosolids represent a significant reservoir of antibiotic resistance genes (ARGs). While current biosolids treatment technologies can reduce ARG levels in residual wastewater biosolids, observed removal rates vary substantially.
Kappell, Anthony D.+2 more
core +1 more source
The Bacteroides mobilizable insertion element, NBU1, integrates into the 3' end of a Leu-tRNA gene and has an integrase that is a member of the lambda integrase family [PDF]
Nadja B. Shoemaker+2 more
openalex +1 more source
Abstract Introduction Pre‐ and post‐exposure prophylaxis (PrEP and PEP) are important pillars of the HIV prevention portfolio to reduce the risk of acquisition just before or after HIV exposure. While PrEP efficacy has been elucidated in many randomized clinical trials, corresponding data for PEP is extremely difficult to obtain in a controlled setting.
Lanxin Zhang+3 more
wiley +1 more source
The core domain of retrotransposon integrase in Hordeum: predicted structure and evolution [PDF]
A. Suoniemi+4 more
openalex +1 more source
Abstract Introduction Islatravir (ISL) is a nucleoside reverse transcriptase translocation inhibitor (NRTTI) with robust antiretroviral activity. The efficacy of ISL administered for post‐exposure prophylaxis (PEP) was evaluated in a simian immunodeficiency virus (SIV) rhesus macaque intravenous (IV) challenge model. Methods Twelve rhesus macaques were
Martin Markowitz+10 more
wiley +1 more source
Abstract Introduction Data on drug resistance, viral outcomes and guidelines compliance following protease inhibitor (PI)‐based second‐line failure in low‐ and middle‐income countries are limited, particularly in the era of dolutegravir‐containing antiretroviral therapy (ART). Methods We conducted a retrospective cohort study of people living with HIV (
John M. Humphrey+11 more
wiley +1 more source
Genomic Heterogeneity in a Natural Archaeal Population Suggests a Model of tRNA Gene Disruption [PDF]
FUJISHIMA, Kosuke+15 more
core +1 more source
Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type- integrase [PDF]
Abhijit Mazumder, Yves Pommier
openalex +1 more source