Results 151 to 160 of about 31,823 (275)

Effect of Pyrolysis on the Removal of Antibiotic Resistance Genes and Class I Integrons from Municipal Wastewater Biosolids [PDF]

open access: yes, 2018
Wastewater biosolids represent a significant reservoir of antibiotic resistance genes (ARGs). While current biosolids treatment technologies can reduce ARG levels in residual wastewater biosolids, observed removal rates vary substantially.
Kappell, Anthony D.   +2 more
core   +1 more source

Modelling the impact of initiation delay, duration and prior PrEP on the efficacy of post‐exposure prophylaxis containing a tenofovir/emtricitabine backbone

open access: yesJournal of the International AIDS Society, Volume 28, Issue S1, 25 June.
Abstract Introduction Pre‐ and post‐exposure prophylaxis (PrEP and PEP) are important pillars of the HIV prevention portfolio to reduce the risk of acquisition just before or after HIV exposure. While PrEP efficacy has been elucidated in many randomized clinical trials, corresponding data for PEP is extremely difficult to obtain in a controlled setting.
Lanxin Zhang   +3 more
wiley   +1 more source

The core domain of retrotransposon integrase in Hordeum: predicted structure and evolution [PDF]

open access: bronze, 1998
A. Suoniemi   +4 more
openalex   +1 more source

Effectiveness of islatravir post‐exposure prophylaxis after intravenous challenge with simian immunodeficiency virus in rhesus macaques

open access: yesJournal of the International AIDS Society, Volume 28, Issue 6, June 2025.
Abstract Introduction Islatravir (ISL) is a nucleoside reverse transcriptase translocation inhibitor (NRTTI) with robust antiretroviral activity. The efficacy of ISL administered for post‐exposure prophylaxis (PEP) was evaluated in a simian immunodeficiency virus (SIV) rhesus macaque intravenous (IV) challenge model. Methods Twelve rhesus macaques were
Martin Markowitz   +10 more
wiley   +1 more source

Substrate specificity of Ty1 integrase [PDF]

open access: bronze, 1995
S P Moore   +2 more
openalex   +1 more source

HIV drug resistance, early treatment outcomes and impact of guidelines compliance after protease inhibitor‐based second‐line failure in a dedicated resistance clinic in western Kenya: a retrospective cohort study

open access: yesJournal of the International AIDS Society, Volume 28, Issue 6, June 2025.
Abstract Introduction Data on drug resistance, viral outcomes and guidelines compliance following protease inhibitor (PI)‐based second‐line failure in low‐ and middle‐income countries are limited, particularly in the era of dolutegravir‐containing antiretroviral therapy (ART). Methods We conducted a retrospective cohort study of people living with HIV (
John M. Humphrey   +11 more
wiley   +1 more source

Genomic Heterogeneity in a Natural Archaeal Population Suggests a Model of tRNA Gene Disruption [PDF]

open access: yes, 2012
FUJISHIMA, Kosuke   +15 more
core   +1 more source

Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

open access: bronze, 1992
Robert L. LaFemina   +7 more
openalex   +1 more source

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