Results 111 to 120 of about 311,604 (320)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Reliable Integrated Photonic Light Sources Using Curved Al2O3:Er3+ Distributed Feedback Lasers
IEEE Photonics Journal, 2017 We propose a curved erbium doped aluminum oxide (Al2O3:Er3+) distributed feedback (DFB) laser for a reliable integrated photonics light source. The curved structure allows us for compensation of the radially varying film thickness due to the Al2O3:
Nanxi Li +8 more
doaj +1 more source
Noise and resolution in IO interferometric sensing [PDF]
, 2007 The paper presents a general theory for sensing devices, relating noise and device parameters to resolution of modal index changes. The theory is applied to optimise the length of a few integrated optics sensing devices, being a Mac-Zehnder ...
Hoekstra, H.J.W.M. +3 more
core +1 more source
Towards integrated superconducting detectors on lithium niobate waveguides
, 2017 Superconducting detectors are now well-established tools for low-light optics, and in particular quantum optics, boasting high-efficiency, fast response and low noise.
Bartley, Tim J. +17 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Investigation of direct integrated optics modulators [PDF]
Direct optical modulation techniques applicable to integrated optical data preprocessors were studied. Emphasis was placed on the analysis and fabrication of a field effect type modulator. A series of computer modeling studies were performed to determine
Batchman, T. E., Mcwright, G. M.
core +1 more source
Dispersion-enabled quantum state control in integrated photonics
, 2016 Integrated optics has brought unprecedented levels of stability and performance to quantum photonic circuits. However, integrated devices are not merely micron-scale equivalents of their bulk-optics counterparts.
Helmy, Amr S., Marchildon, Ryan P.
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Focus on integrated quantum optics
New Journal of Physics, 2013 A key goal of research into quantum information processing is the development of technologies that are scaleable in complexity while allowing the mass manufacture of devices that promise transformative effects on information science.
Jeremy O'Brien +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source