Results 91 to 100 of about 6,158,970 (292)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Describing the “Integrated” in Integrated Ecosystem Assessments
, 2014 No abstracts are to be cited without prior reference to the author. Within the Theme Session: “One size does not fit all – what does an Integrated Ecosystem Assessment mean to YOU?”, multiple perspectives on, approaches to, and interpretations of an ...
M. Robin Anderson (17664423) +2 more
core +1 more source
Inquiry: The Journal of Health Care Organization, Provision, and FinancingBackground Digital health systems can improve healthcare delivery in low-resource settings but are often constrained by unreliable electricity and inadequate infrastructure.
Ronald Danny Nyatuka +2 more
doaj +1 more source
Integrated Water Resource Assessment of Irrigation System of Haryana
Agricultural Sciences, 2018 Agriculture is the major activity in the state of Haryana and large volume of water is required to meet the irrigation demands of the crops grown. But, there is limited water availability in the state. Haryana receives water from Yamuna River and Bhakra system. Sowmelt, rainfall and groundwater are main sources of water in the catchment.
Shiv Singh Rawat +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Integrated Resource Efficiency: Measurement and Management [PDF]
, 2016 Drawing on the Systems Theory and the Natural Resource Based View, this paper advances an Integrated Resource Efficiency View (IREV) and derives a composite ‘Integrated Resource Efficiency Index’ (IRE-Index) for assessing the environmental, economic, and
Morris, J. +7 more
core +1 more source
MicroorganismsGlobal wastewater generated in unprecedented volumes places a significant strain on aquatic environments, challenging the municipal sector to transition from energy-heavy pollutant removal technologies towards alternative resource recovery strategies ...
Alexandru Vlaicu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
EURASIP Journal on Wireless Communications and NetworkingThe integrated sensing and communications (ISC) application completely changes the game regarding collecting, analyzing, and dispensing facts in real time via combining sensing skills with communication structure. The present research delves into how ISC
Manochandar Subramaniyan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source