Results 111 to 120 of about 134,683 (295)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A Systems Thinking and Design Thinking Approach to Leadership

Expert Journal of Business and Management, 2019
Systems Thinking, Design Thinking and Leadership have largely been developed independently of each other. More recently, there have been, ongoing initiatives to integrate Systems Thinking and Design Thinking.
Grace MUGADZA, Roy MARCUS
doaj  

The effect of PBL integrated RMS on biological literacy and critical thinking ability of high school students

JPBI (Jurnal Pendidikan Biologi Indonesia)
This study aimed to determine the effect of Problem-Based Learning (PBL) integrated Reading, Mind Mapping, and Sharing (RMS) on biological literacy and critical thinking skills in biotechnology material.
Khairotun Nihlah, Rizhal Hendi Ristanto, Tri Handayani Kurniati   +2 more
doaj   +1 more source

Integrating design thinking into dental education

Frontiers in Oral Health
Design thinking is a human-centred, iterative process that aims to develop innovative solutions tailored to user needs. This article examines the groundwork and incorporation of design thinking in healthcare and medical education, highlighting its potential benefits in dental education, including enhancements in learner-centred approaches, faculty ...
Supachai Chuenjitwongsa, Lisa R. Amir, Abbas Jessani, Abbas Jessani, Lakshman P. Samaranayake, Lakshman P. Samaranayake, Thanaphum Osathanon, Thanaphum Osathanon   +7 more
openaire   +3 more sources

Revealing integrated thinking through integrated reporting: an exploratory study within an Australian context

, 2016
Whilst integrated thinking is a core concept within the integrated reporting framework issued by the IIRC, it remains unclear how stakeholders and practitioners understand this concept in either theory or practice.
Tianyuan Feng (12305927)
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

DEVELOPMENT OF ETHNOSCIENCE INTEGRATED E-WORKSHEET IN ACID BASE MATERIALS TO IMPROVE CRITICAL THINKING SKILL

EDUSAINS
Critical thinking skills are one of the skills needed in the current era of education. The ability to think critically is an important key for students in successful problem solving.
Indra Adia Kusuma, Woro Sumarni
doaj   +1 more source

Integrated Reporting og Integrated Thinking

, 2017
I løbet af de sidste to måneder af 2016, havde vi mulighed for at deltage i to konferencer, med fokus på at udvikle og fremme ‘Integrated Reporting’ (IR) og ‘Integrated Thinking’.
Sonnerfeldt, Amanda, Aggestam Pontoppidan, Caroline   +1 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Är Integrated Thinking framgångsreceptet? : En studie om arbetsmiljö och dess betydelse för Integrated Thinking

, 2018
Integrated Thinking är en ny trend inom företagsstyrning. Begreppet är dock mångtydigt och det råder oklarheter i hur organisationer kan nå Integrated Thinking. Studien ämnade att konkretisera begreppets innebörd.
Mankowitz, Johanna, Vickers, Emelie
core