Results 91 to 100 of about 109,415 (265)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The effect of culturally-integrated TEE model teaching materials on secondary school students’ critical thinking skills and cultural literacy competence

open access: yesFrontiers in Education
This study examines the effect of culturally integrated TEE model-based Pancasila and Civic Education teaching materials on students’ critical thinking and cultural literacy competence and explores differences in students’ critical thinking and cultural ...
Lalu Sumardi   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A Systems Thinking and Design Thinking Approach to Leadership

open access: yesExpert Journal of Business and Management, 2019
Systems Thinking, Design Thinking and Leadership have largely been developed independently of each other. More recently, there have been, ongoing initiatives to integrate Systems Thinking and Design Thinking.
Grace MUGADZA, Roy MARCUS
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

DEVELOPMENT OF ETHNOSCIENCE INTEGRATED E-WORKSHEET IN ACID BASE MATERIALS TO IMPROVE CRITICAL THINKING SKILL

open access: yesEDUSAINS
Critical thinking skills are one of the skills needed in the current era of education. The ability to think critically is an important key for students in successful problem solving.
Indra Adia Kusuma, Woro Sumarni
doaj   +1 more source

Integrating design thinking into dental education

open access: yesFrontiers in Oral Health
Design thinking is a human-centred, iterative process that aims to develop innovative solutions tailored to user needs. This article examines the groundwork and incorporation of design thinking in healthcare and medical education, highlighting its potential benefits in dental education, including enhancements in learner-centred approaches, faculty ...
Supachai Chuenjitwongsa   +7 more
openaire   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The effect of PBL integrated RMS on biological literacy and critical thinking ability of high school students

open access: yesJPBI (Jurnal Pendidikan Biologi Indonesia)
This study aimed to determine the effect of Problem-Based Learning (PBL) integrated Reading, Mind Mapping, and Sharing (RMS) on biological literacy and critical thinking skills in biotechnology material.
Khairotun Nihlah   +2 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

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