Results 81 to 90 of about 134,683 (295)

Analysis of Threaded-Type Integrated Learning Model in Developing Creativity and Critical Thinking

Pena Anda
Teaching and learning activities in elementary schools prioritize mastery of material or theory-based. This research aims to evaluate the effectiveness of the Threaded-type integrated learning model in developing the creative thinking skills of ...
Zaza Bella Ummi Rahmah, Ratu Bulkis Kamaliyah   +1 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Translation of Integrated Reporting and Integrated Thinking

, 2021
This study explored the operationalisation of integrated reporting (IR), the latest corporate reporting technology, in one of the largest financial institutions in Australia.
Sumon Bhattacharjee (15189805)
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Redefining Healthcare Infrastructure: Moving Toward Integrated Solutions

, 2010
Currently in the United Kingdom there is a trend to broaden the scope of service provision in the healthcare sector. Not only are new healthcare-related services being provided to the community, but also there is increasing concern for providing ...
Formoso, Carlos Torres, Tillmann, P, Formoso, C, Tillmann, Patricia, Tzortzopoulos, Patricia, Tzortzopoulos, P   +5 more
core  

Making sustainable development goals happen through integrated thinking and reporting

, 2020
This chapter analyses the role that organizations can play in the achievement of the UN Sustainable Development Goals (SDGs). Drawing on the experience of three corporate leaders in different industries, we analyse the role that organizations can play in
Federica Izzo, Busco Cristiano, Granà Fabrizio   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Effectiveness of Integrated Interactive Problem Based Learning E-Modules in Improving Critical Thinking Abilities

Jurnal Paedagogy
This study aims to analyze the improvement of students' critical thinking skills by using interactive modules integrated with problem-based learning on the excretory system material.
Afreni Hamidah, Hawalya Hawalya, M. Erick Sanjaya   +2 more
doaj   +1 more source

An assessment of integrated thinking levels among JSE-listed entities

, 2022
A research report submitted in partial fulfilment of the requirements for the degree of Master of Commerce (Accounting), Faculty of Commerce, Law and Management, School of AccountancyIntegrated thinking involves a holistic, multi-capital approach to ...
Ecim, Dusan
core