Results 61 to 70 of about 134,683 (295)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Analysis of Religious Characters and Logical Thinking Skills After Using Solar System Teaching Material Integrated with Islamic Science

open access: yesJournal of Innovation in Educational and Cultural Research, 2020
This study aims to analyze the religious character and logical thinking skills of students after using solar systems teaching materials integrated with Islamic Science.
Eka Yulida Fitriani, Fidia Fibriana
doaj   +1 more source

Integrating computational thinking into english writing: development of a computational thinking-integrated module

open access: yesJournal of Education and Learning (EduLearn)
This study addresses challenges in teaching English writing skills in English as a second language (ESL) classrooms, proposing a novel approach through computational thinking (CT). A CT-integrated writing module was developed for primary school ESL teachers using the analysis, design, development, implementation, and evaluation (ADDIE) model and ...
Aslina Saad   +2 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Decision-making for climate change adaptation: A systems thinking approach [PDF]

open access: yes, 2013
The impacts of climate change are exacerbated by inefficient adaptation and mitigation decision making, due to the complexity of the decision-making environment. As a consequence, there is no single approach to planning and decision making.
Kambiz Maani, Maani, Kambiz
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Integrated Thinking: Concept, Measurement and Economic Benefits

open access: yes, 2023
Stakeholders are demanding more information about how organisations create value. This has led to rapid developments in corporate reporting, particularly the provision of non-financial information relating to an organisation’s sustainability.
Dimes, Ruth Annabel Joan
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Development of Multiliteration and Higher Order Thinking Skills Through Integrated Learning

open access: yesInternational Journal of Science and Applied Science: Conference Series, 2019
This paper aims to describe integrated learning as a learning approach, which is suggested to be applied in order to develop multiliteration and higher order thinking skills.
Kurniasih Kurniasih
doaj   +1 more source

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