Results 61 to 70 of about 134,683 (295)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
This study aims to analyze the religious character and logical thinking skills of students after using solar systems teaching materials integrated with Islamic Science.
Eka Yulida Fitriani, Fidia Fibriana
doaj +1 more source
This study addresses challenges in teaching English writing skills in English as a second language (ESL) classrooms, proposing a novel approach through computational thinking (CT). A CT-integrated writing module was developed for primary school ESL teachers using the analysis, design, development, implementation, and evaluation (ADDIE) model and ...
Aslina Saad +2 more
openaire +2 more sources
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Decision-making for climate change adaptation: A systems thinking approach [PDF]
The impacts of climate change are exacerbated by inefficient adaptation and mitigation decision making, due to the complexity of the decision-making environment. As a consequence, there is no single approach to planning and decision making.
Kambiz Maani, Maani, Kambiz
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Integrated Thinking: Concept, Measurement and Economic Benefits
Stakeholders are demanding more information about how organisations create value. This has led to rapid developments in corporate reporting, particularly the provision of non-financial information relating to an organisation’s sustainability.
Dimes, Ruth Annabel Joan
core
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Development of Multiliteration and Higher Order Thinking Skills Through Integrated Learning
This paper aims to describe integrated learning as a learning approach, which is suggested to be applied in order to develop multiliteration and higher order thinking skills.
Kurniasih Kurniasih
doaj +1 more source

