Results 51 to 60 of about 134,683 (295)

Improving construction design : The lean thinking paradigm [PDF]

open access: yes, 1999
A study has been conducted into improving construction design through the application of the lean thinking paradigm. Its objective was to identify the issues relating to design efficiency and how a lean thinking approach might address these issues ...
Morris, J., Morris, Jonathan
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Integrated Thinking and Reporting [PDF]

open access: yes, 2016
This introductory guide has been developed by the International Integrated Reporting Council (IIRC), the Chartered Institute of Public Finance and Accountancy (CIPFA) with the support of the World Bank to explain to public sector leaders and their teams how integrated thinking and reporting can help the sector consider how make the most of resources ...
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An integrative model of perseverative thinking

open access: yesDialogues in Clinical Neuroscience
People spend most of their waking hours detached from external stimuli, remembering the past, foreseeing the future, imagining situations in which they did not attend or that have never existed, or, simply, thinking. Such a process is crucial for mental health.
Mattioni, Lorenzo   +4 more
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

National concept for the development of integrated reporting in Russia

open access: yesУчёт. Анализ. Аудит
The growing attention of the state to the issues of national sovereignty in different areas has predetermined the urgency of considering the current state of affairs in the field of corporate reporting from this position.
N. V. Malinovskaya
doaj   +1 more source

The integrated reporting system: a new accountability enhancement tool for public sector entities

open access: yesAudit Financiar, 2016
In the recent years, integrated reporting has made progress towards becoming an efficient communication instrument that would bring an active contribution to the financial stability and sustainability of the economic environment.
Tudor Oprişor   +2 more
doaj   +1 more source

Introduction : Thinking Integration Otherwise

open access: yes, 2023
peerReviewed
Ennser-Kananen, Johanna   +5 more
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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