Results 91 to 100 of about 1,936,839 (295)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Polynomial Inverse Integrating Factors, First Integral and Non-Existence of Limit Cycles in the Plane for Quadratic Systems

Science Journal of University of Zakho, 2017
The main purpose of this paper is to study the existence of polynomial inverse integrating factor and first integral, and non-existence of limit cycles for all systems. Furthermore, we consider some applications.
Ahmed M. Hussien
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structures of Single-stage and High Power Factor Electronic Ballasts Integrating the Boost and Ballast Inductors

Eletrônica de Potência, 2013
This paper presents a new family of high power factor for electronic ballasts applied to fluorescent lamps. From the proposed structures, two topologies are presented without the ballast inductor, because the boost inductor, in addition to performing ...
Claudinor B. Nascimento, Marcos A. I. Martins, Mauricio S. Kaster, Arnaldo J. Perin   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Secure Internet Financial Transactions: A Framework Integrating Multi-Factor Authentication and Machine Learning

AI
Securing online financial transactions has become a critical concern in an era where financial services are becoming more and more digital. The transition to digital platforms for conducting daily transactions exposed customers to possible risks from ...
AlsharifHasan Mohamad Aburbeian, Manuel Fernández-Veiga   +1 more
doaj   +1 more source

Integrating certainty factor into a web-based expert system for intelligent diagnosis of chili plant pathologies [PDF]

BIO Web of Conferences
Chili pepper plant diseases are a major problem that can reduce yield and quality. Farmers face difficulties in diagnosing chili plant diseases due to limited knowledge and resources.
Wibowo Nugroho Setyo, Dhamayanthi Wenny, Saputra Restu Aji Prasetyo, Rizky Dian, Dewangga Vigo   +4 more
doaj   +1 more source

Economic Integration and Welfare: Manufacturing vs. Agricultural Markets [PDF]

In the literature of new trade theory, most papers study the industrial location by imposing the assumption of free transportation in the agricultural sector.
Dao-Zhi Zeng, Hajime Takatsuka
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Integrating CVSS, national criticality levels, and MCDA for multi-factor cyber incident prioritization

Радіоелектронні і комп'ютерні системи
This integrated approach aims to prevent suboptimal prioritization, ensure effective resource allocation, and expedite the recovery of information systems.
Dmytro Uzlov, Sergiy Yakovlev, Olena Tolstoluzka, Oleksandr Kopytsia, Sergiy Burchenko   +4 more
doaj   +1 more source