Results 111 to 120 of about 7,935,126 (334)

A driving feel oriented dynamic model for commercial vehicles

open access: yesScientific Reports
Virtual testing and evaluation of commercial vehicles require an accurate and comprehensive dynamic model to replace traditional driver-based field testing, thereby shortening the development cycle of commercial vehicles. However, existing dynamic models
Li Li   +4 more
doaj   +1 more source

Influence of external environment on thermal environment of cabin and optimization of air supply strategy of air conditioner

open access: yesResults in Engineering
This paper employs CFD software to establish a mathematical model of a full-vehicle environmental wind tunnel, and couples it with the Berkeley thermal comfort evaluation model to assess human thermal comfort. The study investigates the impact of varying
Yingchao Zhang   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

INTEGRATION OF PARTIALLY INTEGRABLE EQUATIONS [PDF]

open access: yesWaves and Stability in Continuous Media, 2006
12 p, WASCOM XIII (Acireale, 19-25 June 2005)
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Si-Ge-Silica Monolithic Integration Platform and Its Application to a 22-Gb/s $\times$ 16-ch WDM Receiver

open access: yesIEEE Photonics Journal, 2013
We describe a Si-Ge-silica monolithic integration platform for telecommunications applications. The monolithic integration process features low-temperature silica film deposition by electron-cyclotron-resonance chemical vapor deposition to prevent ...
Tatsurou Hiraki   +8 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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