Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Special Issue: "Molecular Diagnosis and Treatments of Diabetes Mellitus". [PDF]
Boldeanu MV.
europepmc +1 more source
This study demonstrates that pulsed potential electrolysis significantly improves CO2 reduction performance on copper‐nitrogen doped carbon electrodes. The formation of cationic copper sites and metallic clusters as a function of applied intermittent potential leads to notable selectivity changes compared to potentiostatic reduction.
Dorottya Hursán +13 more
wiley +1 more source
Unifying pharmacology, systems biology, and regenerative medicine to advance personalized therapies. [PDF]
Martins A.
europepmc +1 more source
DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim +13 more
wiley +1 more source
Interoception as a central mechanism in Whole Person Health. [PDF]
Chen WG, Langevin HM.
europepmc +1 more source
Electroactive Metal–Organic Frameworks for Electrocatalysis
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska +7 more
wiley +1 more source
RCSB Protein Data Bank: Delivering integrative structures alongside experimental structures and computed structure models. [PDF]
Vallat B +25 more
europepmc +1 more source
Reevaluating the Activity of ZIF‐8 Based FeNCs for Electrochemical Ammonia Production
Though receiving much attention, the field of electrochemical nitrogen reduction reaction (eNRR) to ammonia is marked by doubts about whether this reaction is possible in aqueous media. This work sheds light on this question for iron single‐atom on N‐doped carbon (FeNC) catalysts—a class of well‐known catalysts that is also worth testing for the sister
Caroline Schneider +6 more
wiley +1 more source
Editorial: <i>Acta Biochimica Polonica</i> reviews | 2023-2024. [PDF]
Rurek M +6 more
europepmc +1 more source

