Results 1 to 10 of about 983,499 (150)

Mouse models in colon cancer, inferences, and implications

iScience, 2023
Summary: Mouse models of colorectal cancer (CRC) have been crucial in the identification of the role of genes responsible for the full range of pathology of the human disease and have proved to be dependable for testing anti-cancer drugs. Recent research
Melanie Haas Kucherlapati
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SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis

iScience, 2022
Summary: Recent studies showed that SARS-CoV-2 can infect adult human pancreas and trigger pancreatic damage. Here, using human fetal pancreas samples and 3D differentiation of human pluripotent cells into pancreatic endocrine cells, we determined that ...
Wojciech J. Szlachcic, Agnieszka Dabrowska, Aleksandra Milewska, Natalia Ziojla, Katarzyna Blaszczyk, Emilia Barreto-Duran, Marek Sanak, Marcin Surmiak, Katarzyna Owczarek, Dariusz Grzanka, Julia Durzynska, Krzysztof Pyrc, Malgorzata Borowiak   +12 more
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Lagomorpha as a Model Morphological System

Frontiers in Ecology and Evolution, 2021
Due to their global distribution, invasive history, and unique characteristics, European rabbits are recognizable almost anywhere on our planet. Although they are members of a much larger group of living and extinct mammals [Mammalia, Lagomorpha (rabbits,
Brian Kraatz, Rafik Belabbas, Łucja Fostowicz-Frelik, Łucja Fostowicz-Frelik, Łucja Fostowicz-Frelik, De-Yan Ge, Alexander N. Kuznetsov, Madlen M. Lang, Sergi López-Torres, Sergi López-Torres, Sergi López-Torres, Zeinolabedin Mohammadi, Rachel A. Racicot, Rachel A. Racicot, Matthew J. Ravosa, Alana C. Sharp, Emma Sherratt, Mary T. Silcox, Justyna Słowiak, Alisa J. Winkler, Alisa J. Winkler, Irina Ruf   +21 more
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Sperm Accumulation Induced by the Female Reproductive Fluid: Putative Evidence of Chemoattraction Using a New Tool

Cells, 2021
There is considerable evidence that female reproductive fluid (FRF) interacts intimately with sperm, affecting several sperm traits, including sperm motility and longevity, and ultimately fertilization success.
Alessandro Devigili, Silvia Cattelan, Clelia Gasparini   +2 more
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Unconventional Myosins from Caenorhabditis elegans as a Probe to Study Human Orthologues

Biomolecules, 2022
Unconventional myosins are a superfamily of actin-based motor proteins that perform a number of roles in fundamental cellular processes, including (but not limited to) intracellular trafficking, cell motility, endocytosis, exocytosis and cytokinesis.
Chloe A Johnson, Ranya Behbehani, Folma Buss   +2 more
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A Caenorhabditis elegans Model for Integrating the Functions of Neuropsychiatric Risk Genes Identifies Components Required for Normal Dendritic Morphology

G3: Genes, Genomes, Genetics, 2020
Analysis of patient-derived DNA samples has identified hundreds of variants that are likely involved in neuropsychiatric diseases such as autism spectrum disorder (ASD) and schizophrenia (SCZ).
Cristina Aguirre-Chen, Natalia Stec, Olivia Mendivil Ramos, Nuri Kim, Melissa Kramer, Shane McCarthy, Jesse Gillis, W. Richard McCombie, Christopher M. Hammell   +8 more
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Why Protect Decapod Crustaceans Used as Models in Biomedical Research and in Ecotoxicology? Ethical and Legislative Considerations

Animals, 2021
Decapod crustaceans are widely used as experimental models, due to their biology, their sensitivity to pollutants and/or their convenience of collection and use.
Annamaria Passantino, Robert William Elwood, Paolo Coluccio   +2 more
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A Multilevel Study of Eupatorin and Scutellarein as Anti-Amyloid Agents in Alzheimer’s Disease

Biomedicines, 2023
Today, Alzheimer’s disease (AD)—the most common neurodegenerative disorder, which affects 50 million people—remains incurable. Several studies suggest that one of the main pathological hallmarks of AD is the accumulation of abnormal amyloid beta (Aβ ...
Aikaterini E. I. Rizou, Georgia I. Nasi, Yiorgos Paikopoulos, Dimitra S. Bezantakou, Konstantina D. Vraila, Panagiotis M. Spatharas, Virginia D. Dimaki, Nikos C. Papandreou, Fotini N. Lamari, Niki Chondrogianni, Vassiliki A. Iconomidou   +10 more
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EcoCyc: fusing model organism databases with systems biology. [PDF]

, 2012
EcoCyc (http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E.
Bonavides-Martínez, César, Collado-Vides, Julio, Fulcher, Carol, Gama-Castro, Socorro, Gunsalus, Robert P, Huerta, Araceli M, Karp, Peter D, Keseler, Ingrid M, Kothari, Anamika, Krummenacker, Markus, Latendresse, Mario, Mackie, Amanda, Muñiz-Rascado, Luis, Ong, Quang, Paley, Suzanne, Paulsen, Ian, Peralta-Gil, Martin, Santos-Zavaleta, Alberto, Schröder, Imke, Shearer, Alexander G, Subhraveti, Pallavi, Travers, Mike, Weerasinghe, Deepika, Weiss, Verena   +23 more
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Effects of altered gravity induced by clinorotation on the cholinesterase activity of the non-sentient model Paramecium primaurelia (Protozoa)

Journal of Biological Research, 2018
Compounds known as chemical mediators, including acetylcholine, have been found not only in humans and animals, but also in living organisms, like protozoa, which lack nervous system.
Francesca Sardi, Martina Rossi, Sara Ferrando, Maria Angela Masini, Federico Biggi, Andrea Amaroli   +5 more
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