Results 1 to 10 of about 8,788 (117)
Mouse models in colon cancer, inferences, and implications
iScience, 2023 Summary: Mouse models of colorectal cancer (CRC) have been crucial in the identification of the role of genes responsible for the full range of pathology of the human disease and have proved to be dependable for testing anti-cancer drugs. Recent research
Melanie Haas Kucherlapati
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SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis
iScience, 2022 Summary: Recent studies showed that SARS-CoV-2 can infect adult human pancreas and trigger pancreatic damage. Here, using human fetal pancreas samples and 3D differentiation of human pluripotent cells into pancreatic endocrine cells, we determined that ...
Wojciech J. Szlachcic +12 more
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Lagomorpha as a Model Morphological System
Frontiers in Ecology and Evolution, 2021 Due to their global distribution, invasive history, and unique characteristics, European rabbits are recognizable almost anywhere on our planet. Although they are members of a much larger group of living and extinct mammals [Mammalia, Lagomorpha (rabbits,
Brian Kraatz +21 more
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Cells, 2021 There is considerable evidence that female reproductive fluid (FRF) interacts intimately with sperm, affecting several sperm traits, including sperm motility and longevity, and ultimately fertilization success.
Alessandro Devigili +2 more
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Non-model model organisms [PDF]
BMC Biology, 2017 Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but modern research tools are enabling researchers to extend the set of model organisms to include less-studied and more unusual systems.
Russell, James J +18 more
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A Fetching Model Organism [PDF]
Cell, 2006 The creation of the domestic dog and its many breeds has been an ongoing experiment in the rapid evolution of form and function. Now, advances in genomics have made Canis familiaris genetically tractable and poised to offer insights into evolution, development, and behavior.
Neff, Mark W., Rine, Jasper
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Unconventional Myosins from Caenorhabditis elegans as a Probe to Study Human Orthologues
Biomolecules, 2022 Unconventional myosins are a superfamily of actin-based motor proteins that perform a number of roles in fundamental cellular processes, including (but not limited to) intracellular trafficking, cell motility, endocytosis, exocytosis and cytokinesis.
Chloe A Johnson +2 more
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G3: Genes, Genomes, Genetics, 2020 Analysis of patient-derived DNA samples has identified hundreds of variants that are likely involved in neuropsychiatric diseases such as autism spectrum disorder (ASD) and schizophrenia (SCZ).
Cristina Aguirre-Chen +8 more
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Animals, 2021 Decapod crustaceans are widely used as experimental models, due to their biology, their sensitivity to pollutants and/or their convenience of collection and use.
Annamaria Passantino +2 more
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A Multilevel Study of Eupatorin and Scutellarein as Anti-Amyloid Agents in Alzheimer’s Disease
Biomedicines, 2023 Today, Alzheimer’s disease (AD)—the most common neurodegenerative disorder, which affects 50 million people—remains incurable. Several studies suggest that one of the main pathological hallmarks of AD is the accumulation of abnormal amyloid beta (Aβ ...
Aikaterini E. I. Rizou +10 more
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