Results 31 to 40 of about 983,648 (296)
The Chlamydomonas genome project: A decade on [PDF]
, 2014 The green alga Chlamydomonas reinhardtii is a popular unicellular organism for studying photosynthesis, cilia biogenesis, and micronutrient homeostasis.
Aksoy, M +19 more
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Non-mammalian model organisms in epigenetic research : an overview [PDF]
, 2020 Recent advances in sequencing technology and genome editing tools had an indisputably enormous impact on our understanding of complex biological pathways and their genetic and epigenetic regulation.
Baruah, Sri Kartik +3 more
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模式生物斑马鱼在卒中研究中的应用Application of Zebrafish Model Organism in Stroke Research
Zhongguo cuzhong zazhi, 2022 Animal model provides a necessary tool for exploring the complex pathophysiological process of cerebrovascular disease and drug development. Zebrafish (Danio rerio) is an ideal spinal model organism, which has the characteristics of small size, strong ...
莫东灿, 刘柳余, 李肖玲, 李建立, 罗曼
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Veterinary Sciences, 2017 Congenital heart defects, clinically identified in both small and large animals, are multifactorial and complex. Although heritable factors are known to have a role in cardiovascular disease, the full genetic aetiology remains unclear.
Jessica Vanderploeg, J. Roger Jacobs
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Frontiers in ImmunologyIntroductionThe new targeted gene editing technologies, such as the CRISPR/Cas system, enable researchers to insert or delete genes at targeted loci efficiently.
Yang Guo +7 more
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Population–reaction model and microbial experimental ecosystems for understanding hierarchical dynamics of ecosystems [PDF]
, 2016 Understanding ecosystem dynamics is crucial as contemporary human societies face ecosystem degradation. One of the challenges that needs to be recognized is the complex hierarchical dynamics.
Hosoda, Kazufumi +3 more
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Metabolic network modeling with model organisms [PDF]
Current Opinion in Chemical Biology, 2017 Flux balance analysis (FBA) with genome-scale metabolic network models (GSMNM) allows systems level predictions of metabolism in a variety of organisms. Different types of predictions with different accuracy levels can be made depending on the applied experimental constraints ranging from measurement of exchange fluxes to the integration of gene ...
Yilmaz, L. Safak, Walhout, Albertha J M
openaire +3 more sources
Genome-Wide Mutational Signature of the Chemotherapeutic Agent Mitomycin C in Caenorhabditis elegans
G3: Genes, Genomes, Genetics, 2016 Cancer therapy largely depends on chemotherapeutic agents that generate DNA lesions. However, our understanding of the nature of the resulting lesions as well as the mutational profiles of these chemotherapeutic agents is limited.
Annie S. Tam +2 more
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Microfluidic Devices in Advanced Caenorhabditis elegans Research
Molecules, 2016 The study of model organisms is very important in view of their potential for application to human therapeutic uses. One such model organism is the nematode worm, Caenorhabditis elegans. As a nematode, C.
Muniesh Muthaiyan Shanmugam +1 more
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Uberon: towards a comprehensive multi-species anatomy ontology [PDF]
, 2009 The lack of a single unified species-neutral ontology covering the anatomy of a variety of metazoans is a hindrance to translating model organism research to human health.
Chris Mungall +3 more
core +2 more sources