Results 21 to 30 of about 14,465,375 (259)

Generation and characterization of a tamoxifen-inducible lineage tracing tool Cd2-P2A-CreERT2 knock-in mice

open access: yesFrontiers in Immunology
IntroductionThe new targeted gene editing technologies, such as the CRISPR/Cas system, enable researchers to insert or delete genes at targeted loci efficiently.
Yang Guo   +7 more
doaj   +1 more source

模式生物斑马鱼在卒中研究中的应用Application of Zebrafish Model Organism in Stroke Research

open access: yesZhongguo cuzhong zazhi, 2022
Animal model provides a necessary tool for exploring the complex pathophysiological process of cerebrovascular disease and drug development. Zebrafish (Danio rerio) is an ideal spinal model organism, which has the characteristics of small size, strong ...
莫东灿, 刘柳余, 李肖玲, 李建立, 罗曼
doaj   +1 more source

Pseudomonas: Model Organism, Pathogen, Cell Factory

open access: yes, 2008
Concise and up-to-date, this handy guide fills a gap in the literature by providing the essential knowledge for everyone with an interest in the topic.
Rehm, BHA, Rehm, Bernd H.A.
core   +1 more source

Genome-Wide Mutational Signature of the Chemotherapeutic Agent Mitomycin C in Caenorhabditis elegans

open access: yesG3: Genes, Genomes, Genetics, 2016
Cancer therapy largely depends on chemotherapeutic agents that generate DNA lesions. However, our understanding of the nature of the resulting lesions as well as the mutational profiles of these chemotherapeutic agents is limited.
Annie S. Tam   +2 more
doaj   +1 more source

Microfluidic Devices in Advanced Caenorhabditis elegans Research

open access: yesMolecules, 2016
The study of model organisms is very important in view of their potential for application to human therapeutic uses. One such model organism is the nematode worm, Caenorhabditis elegans. As a nematode, C.
Muniesh Muthaiyan Shanmugam   +1 more
doaj   +1 more source

Study of online ticketing behaviour of Premier League spectators: Perspectives from the stimulus-organism-response theory and technology acceptance model [Abstract]

open access: yes
Study of online ticketing behaviour of Premier League spectators: Perspectives from the stimulus-organism-response theory and technology acceptance model [Abstract]
Jacky Mueller (7468301)   +2 more
core   +5 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

What is an organism? An immunological answer [PDF]

open access: yes, 2010
The question “What is an organism?”, formerly considered as essential in biology, has now been increasingly replaced by a larger question, “What is a biological individual?”.
Pradeu, Thomas
core  

Brain-Body Control of Glucose Homeostasis—Insights From Model Organisms

open access: yesFrontiers in Endocrinology, 2021
Tight regulation of blood glucose is essential for long term health. Blood glucose levels are defended by the correct function of, and communication between, internal organs including the gastrointestinal tract, pancreas, liver, and brain.
Alastair J. MacDonald   +4 more
doaj   +1 more source

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