Results 11 to 20 of about 441,526 (266)
Non-model model organisms [PDF]
Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but modern research tools are enabling researchers to extend the set of model organisms to include less-studied and more unusual systems.
Russell, James J +18 more
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A Fetching Model Organism [PDF]
The creation of the domestic dog and its many breeds has been an ongoing experiment in the rapid evolution of form and function. Now, advances in genomics have made Canis familiaris genetically tractable and poised to offer insights into evolution, development, and behavior.
Neff, Mark W., Rine, Jasper
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Contribution of model organism phenotypes to the computational identification of human disease genes
Computing phenotypic similarity helps identify new disease genes and diagnose rare diseases. Genotype–phenotype data from orthologous genes in model organisms can compensate for lack of human data and increase genome coverage.
Sarah M. Alghamdi +2 more
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A hundred spotlights on microbiology: how microorganisms shape our lives
Viral, bacterial, fungal and protozoal biology is of cardi-nal importance for the evolutionary history of life, ecol-ogy, biotechnology and infectious diseases.
Didac Carmona-Gutierrez +7 more
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Photobiomodulation (PBM) is a clinically accepted tool in regenerative medicine and dentistry to improve tissue healing and repair and to restore the functional disability. The current in vitro study aimed to investigate the photobiomodulatory effects of
Reem Hanna +10 more
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New opportunities at the wild frontier
A better understanding of the natural history of model organisms will increase their value as model systems and also keep them at the forefront of research.
Jane Alfred, Ian T Baldwin
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Modeling Congenital Disorders of N-Linked Glycoprotein Glycosylation in Drosophila melanogaster
Protein glycosylation, the enzymatic addition of N-linked or O-linked glycans to proteins, serves crucial functions in animal cells and requires the action of glycosyltransferases, glycosidases and nucleotide-sugar transporters, localized in the ...
Anna Frappaolo +6 more
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Yeast as a Model Organism [PDF]
Yeast have many genes with homologs in humans. Has our understanding of these genes helped our understanding of human biology or disease? In his Perspective, Botstein argues "yes" and, as an example, discusses a report in this week9s issue by Sinclair et al.
D, Botstein, S A, Chervitz, J M, Cherry
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Models of Organic Organization in Montpellier Vitalism [PDF]
The species of vitalism discussed here is a malleable construct, often with a poisonous reputation (but one which I want to rehabilitate), hovering in between the realms of the philosophy of biology, the history of medicine, and the scientific background of the Radical Enlightenment (case in point, the influence of vitalist medicine on Diderot).
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Embryonic development is fascinating to follow and highly engaging and, therefore, lends itself for undergraduate students’ first steps in experimental science.
Jennifer Forecki +2 more
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