Results 11 to 20 of about 441,526 (266)

Non-model model organisms [PDF]

open access: yesBMC Biology, 2017
Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but modern research tools are enabling researchers to extend the set of model organisms to include less-studied and more unusual systems.
Russell, James J   +18 more
openaire   +5 more sources

A Fetching Model Organism [PDF]

open access: yesCell, 2006
The creation of the domestic dog and its many breeds has been an ongoing experiment in the rapid evolution of form and function. Now, advances in genomics have made Canis familiaris genetically tractable and poised to offer insights into evolution, development, and behavior.
Neff, Mark W., Rine, Jasper
openaire   +2 more sources

Contribution of model organism phenotypes to the computational identification of human disease genes

open access: yesDisease Models & Mechanisms, 2022
Computing phenotypic similarity helps identify new disease genes and diagnose rare diseases. Genotype–phenotype data from orthologous genes in model organisms can compensate for lack of human data and increase genome coverage.
Sarah M. Alghamdi   +2 more
doaj   +1 more source

A hundred spotlights on microbiology: how microorganisms shape our lives

open access: yesMicrobial Cell, 2022
Viral, bacterial, fungal and protozoal biology is of cardi-nal importance for the evolutionary history of life, ecol-ogy, biotechnology and infectious diseases.
Didac Carmona-Gutierrez   +7 more
doaj   +1 more source

A Comparative Study Between the Effectiveness of 980 nm Photobiomodulation Delivered by Hand-Piece With Gaussian vs. Flat-Top Profiles on Osteoblasts Maturation

open access: yesFrontiers in Endocrinology, 2019
Photobiomodulation (PBM) is a clinically accepted tool in regenerative medicine and dentistry to improve tissue healing and repair and to restore the functional disability. The current in vitro study aimed to investigate the photobiomodulatory effects of
Reem Hanna   +10 more
doaj   +1 more source

New opportunities at the wild frontier

open access: yeseLife, 2015
A better understanding of the natural history of model organisms will increase their value as model systems and also keep them at the forefront of research.
Jane Alfred, Ian T Baldwin
doaj   +1 more source

Modeling Congenital Disorders of N-Linked Glycoprotein Glycosylation in Drosophila melanogaster

open access: yesFrontiers in Genetics, 2018
Protein glycosylation, the enzymatic addition of N-linked or O-linked glycans to proteins, serves crucial functions in animal cells and requires the action of glycosyltransferases, glycosidases and nucleotide-sugar transporters, localized in the ...
Anna Frappaolo   +6 more
doaj   +1 more source

Yeast as a Model Organism [PDF]

open access: yesScience, 1997
Yeast have many genes with homologs in humans. Has our understanding of these genes helped our understanding of human biology or disease? In his Perspective, Botstein argues "yes" and, as an example, discusses a report in this week9s issue by Sinclair et al.
D, Botstein, S A, Chervitz, J M, Cherry
openaire   +2 more sources

Models of Organic Organization in Montpellier Vitalism [PDF]

open access: yesEarly Science and Medicine, 2017
The species of vitalism discussed here is a malleable construct, often with a poisonous reputation (but one which I want to rehabilitate), hovering in between the realms of the philosophy of biology, the history of medicine, and the scientific background of the Radical Enlightenment (case in point, the influence of vitalist medicine on Diderot).
openaire   +2 more sources

Trails to Research: an Inquiry-Based Course Using Zebrafish To Provide Research Experience to Tribal College Students

open access: yesJournal of Microbiology & Biology Education, 2023
Embryonic development is fascinating to follow and highly engaging and, therefore, lends itself for undergraduate students’ first steps in experimental science.
Jennifer Forecki   +2 more
doaj   +1 more source

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