Results 41 to 50 of about 983,648 (296)
Stable States of Biological Organisms
, 2009 A novel model of biological organisms is advanced, treating an organism as a self-consistent system subject to a pathogen flux. The principal novelty of the model is that it describes not some parts, but a biological organism as a whole.
A. Lichtenberg +13 more
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Information-Matter Bipolarity of the Human Organism and Its Fundamental Circuits: From Philosophy to Physics/Neurosciences-Based Modeling [PDF]
, 2020 Starting from a philosophical perspective, which states that the living structures are actually a combination between matter and information, this article presents the results on an analysis of the bipolar information-matter structure of the ...
Gaiseanu, Florin
core
Brain-Body Control of Glucose Homeostasis—Insights From Model Organisms
Frontiers in Endocrinology, 2021 Tight regulation of blood glucose is essential for long term health. Blood glucose levels are defended by the correct function of, and communication between, internal organs including the gastrointestinal tract, pancreas, liver, and brain.
Alastair J. MacDonald +4 more
doaj +1 more source
Digital dissection of the model organism Xenopus laevis using contrast-enhanced computed tomography [PDF]
, 2017 The African clawed frog, Xenopus laevis, is one of the most widely used model organisms in biological research. However, the most recent anatomical description of X. laevis was produced nearly a century ago.
Ahn +62 more
core +2 more sources
A future of the model organism model
Molecular Biology of the Cell, 2014 Changes in technology are fundamentally reframing our concept of what constitutes a model organism. Nevertheless, research advances in the more traditional model organisms have enabled fresh and exciting opportunities for young scientists to establish new careers and offer the hope of comprehensive understanding of fundamental processes in life.
openaire +2 more sources
A model of intracellular organization [PDF]
Proceedings of the National Academy of Sciences, 2005 Almost everything we know about biological chemistry comes from experiments on dilute samples of macromolecules (proteins, DNA, RNA, polysaccharides, etc.). By “dilute,” I mean macromolecular concentrations of 10 g per liter or less. Such conditions are astonishingly different from those inside living cells (1, 2).
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Humans as model organisms [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2017 Like every other species, our species is the result of descent with modification under the influence of natural selection; a tip in an increasingly large and deep series of nested clades, as we trace its ancestry back to increasingly remote antecedents.
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Norway rat, from an obnoxious pest to a laboratory pet
eLife, 2020 The laboratory rat was the first mammal domesticated for research purposes. It is descended from wild Norway rats, Rattus norvegicus, which despite their name likely originated in Asia.
Klaudia Modlinska, Wojciech Pisula
doaj +1 more source