Results 131 to 140 of about 196,514 (244)

Beyond MIDAS: An <i>In Silico</i> Study of a Putative Noncanonical C16 Binding Site in αvβ3 Integrin. [PDF]

ACS Omega
de Andrade FDCP, Ferreira E Silva Y, Batista PR, Mendes AN.   +3 more
europepmc   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Region-dependent expression and function of integrin α5β1 in protecting against disc degeneration <i>via</i> autophagy promotion: an <i>ex vivo</i> organ culture model under dynamic mechanical loading. [PDF]

Front Bioeng Biotechnol
Zhan M, Li Z, Chen S, Chen H, Lin S, Sun W, Ling Z, Su P, Cui S, Zou X.   +9 more
europepmc   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

Advanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias, Maxwell J. Munford, Frederik C.H. Masure, Richard J. van Arkel, Reece N Oosterbeek   +4 more
wiley   +1 more source

Integrin αvβ3 is a Potential Therapeutic Target in Cholangiocarcinoma. [PDF]

Int J Med Sci
Wulandari FS, Wang CY, Crawford DR, Yang YN, Then CK, Kumar S, Suk FM, Huang LY, Yang YS, Li ZL, Shih YJ, Tu HT, Wang K, Phu HD, Lin CM, Xuan DTM, Solomon DD, Lin HY, Whang-Peng J.   +18 more
europepmc   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Integrin alpha L: structure, cellular functions, and emerging role in human diseases. [PDF]

Front Immunol
Wang X, Yang G, Chen Y, Zhu F, Lian F, Shen W, Luo D.   +6 more
europepmc   +1 more source

Integrins. [PDF]

Journal of Clinical Investigation, 1991
openaire   +2 more sources

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Kindlins regulate integrin- and growth factor-dependent ureteric bud formation. [PDF]

Development
Li S, Bock F, Viquez O, Hassan A, Mathew S, Palamuttam R, Mernaugh G, Dong X, Melzer M, Tantengco M, Carroll T, Terker A, Arroyo JP, Pozzi A, Zent R.   +14 more
europepmc   +1 more source