Results 181 to 190 of about 304,001 (345)

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng, Aijun Liang, Maximus CF Yeung, Sze Keong Tey, Kam‐Leung Siu, Sin‐Yee Fung, Dong‐Yan Jin, Judy Wai Ping Yam   +7 more
wiley   +1 more source

K562 Chronic Myeloid Leukemia Cells as a Dual β3-Expressing Functional Cell Line Model to Investigate the Effects of Combined αIIbβ3 and αvβ3 Antagonism. [PDF]

Methods Protoc
Elsharif AA, Patterson LH, Shnyder SD, Sheldrake HM.   +3 more
europepmc   +1 more source

“Inside-out” signal transduction inhibited by isolated integrin cytoplasmic domains

, 1994
Y.P. Chen, Timothy E. O’Toole, T. Shipley, Jane Forsyth, Susan E. LaFlamme, Kenneth M. Yamada, Sanford J. Shattil, Mark H. Ginsberg   +7 more
openalex   +1 more source

Fibrinogen induces endothelial cell adhesion and spreading via the release of endogenous matrix proteins and the recruitment of more than one integrin receptor [PDF]

, 1990
Elisabetta Dejana, MG Lampugnani, Marco De Giorgi, Mirella Gáboli, PC Marchisio   +4 more
openalex   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Loss of integrin alpha7-mediated signaling induces a dendritic cell-like phenotype in macrophages cultured on laminin-211/221 isoforms. [PDF]

J Biol Chem
Yoshiba N, Maekawa T, Sekiguchi K, Kaku M, Sirisereephap K, Surboyo M, Sato-Yamada Y, Rosenkranz A, Hosoya A, Ohkura N, Kakihara Y, Maeda T, Hajishengallis G, Izumi K, Yoshiba K.   +14 more
europepmc   +1 more source

Immunolocalization of integrin receptors in normal lymphoid tissues [PDF]

, 1991
MM Zutter
openalex   +1 more source

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

Advanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu, Rockie Haiyao Ding, Zixuan Zhao, Clara Yieh Lin Chong, Ruochii You, Hengjia Zhou, Dong Hua Seah, Wei Qiang Leow, Hong Kit Lim, Sukanya Shyamasundar, Kanishka Fernando, Fathima Farzana Kuthubudeen, Gillian Ng, Chor Yong Tay, Narayanan Gopalakrishna Iyer, Chin‐Ann Johnny Ong, Eliza Li Shan Fong   +16 more
wiley   +1 more source

Retraction: Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Biochemical evidence for a homophilic interaction of the alpha 3 beta 1 integrin.

, 1993
P. Sriramarao, P Steffner, Kurt R. Gehlsen   +2 more
openalex   +1 more source