Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell +6 more
wiley +1 more source
Integrin β1 signaling at the crossroads of cellular plasticity, the tumor microenvironment, and therapy resistance in medulloblastoma. [PDF]
Front OncolEchavidre W, Picco V, Montemagno C.
europepmc +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
JSFA reports, EarlyView.Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
Loss of Pericytic Integrin-β1 Exacerbates Blood-Brain Barrier Damage and Hemorrhagic Brain Injury. [PDF]
StrokeCulha-Taskin I, Nasrollahi A, Yao Y.
europepmc +1 more source
The Early Regenerative Events in the Human Tympanic Membrane After In Vivo Traumatization
The Laryngoscope, EarlyView.At 20 h after in vivo traumatization a regenerative response in the human tympanic membrane is activated. The results show an upregulated proliferation activity in the UPT in early healing and confirm the previously described regenerative regions of the annulus and malleus.
Elnaz Sepehri +5 more
wiley +1 more source
Correction: Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles. [PDF]
J Cell BiolRodrigues-Junior DM +8 more
europepmc +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Roles of integrin β1 and discoidin domain receptor 2 in cranial regeneration and skeletal progenitor cell function. [PDF]
Int J Oral SciHan Y +4 more
europepmc +1 more source
Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley +1 more source
Subcellular Localization of CD24 Is Associated with Integrin β1 Signaling, Immune Suppression, and Clinical Outcomes Across Human Cancers. [PDF]
Biology (Basel)Patel B +4 more
europepmc +1 more source