Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee +10 more
wiley +1 more source
Changes in the Gene Expression of β1 and β2 Integrins Following Development of Tolerance to Analgesic Effect of Morphine in Rats [PDF]
Cell Journal, 2010 Objective: Considering the inhibitory effect of integrin-activity modulator (manganese) onthe development of morphine tolerance; in this study we have tried to assess the effectof chronic administration of both morphine and manganese on the expression ...
Jamal Ghorbi +2 more
doaj
Vascular cell adhesion molecule 1 and alpha 4 and beta 1 integrins in lymphocyte aggregates in Sjogren's syndrome and rheumatoid arthritis. [PDF]
, 1993 Jo C. W. Edwards +3 more
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Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting
Advanced Healthcare Materials, EarlyView.Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari +9 more
wiley +1 more source
Central and peripheral neurite outgrowth differs in preference for heparin-binding versus integrin-binding sequences [PDF]
, 1992 PK Haugen +4 more
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Advanced Healthcare Materials, EarlyView.A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang +9 more
wiley +1 more source
Evidence that the central region of glycoprotein IIIa participates in integrin receptor function [PDF]
, 1991 Priya Ramsamooj +2 more
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Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Immunoreceptors and integrins [PDF]
Immunological Reviews, 2007 Burkhart Schraven, Michael Reth
openaire +3 more sources