eLife, 2016 Integrins require an activation step prior to ligand binding and signaling. How talin and kindlin contribute to these events in non-hematopoietic cells is poorly understood.
Marina Theodosiou +10 more
doaj +1 more source
Immunocytochemical studies of endothelial cells in vivo. II. Chicken aortic and capillary endothelial cells exhibit different cell surface distributions of the integrin complex. [PDF]
, 1988 Takahiro Fujimoto, S. J. Singer
openalex +1 more source
TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel +15 more
wiley +1 more source
Cellular invasion into matrix beads: Localization of fa integrins and fibronectin to the invadopodia [PDF]
, 1991 Susette C. Mueller, Wen‐Tien Chen
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Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Expression of a beta 1-related integrin by oligodendroglia in primary culture: evidence for a functional role in myelination. [PDF]
, 1994 We have investigated the expression of integrins by rat oligodendroglia grown in primary culture and the functional role of these proteins in myelinogenesis.
Malek-Hedayat, S, Rome, LH
core
Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells. [PDF]
, 1992 Anthony J. Pelletier +2 more
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Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella +9 more
wiley +1 more source
Engineering the Rod of Asclepius – A Biochemical Investigation of Snake Venom Components and their Application as Potential Cancer Treatments [PDF]
, 2019 In the wild, venom is crucial to many snakes’ success as predators. While antivenin research focuses on combatting venoms’ abilities to disrupt physiological processes, new studies are attempting to manipulate these same abilities into anticancer ...
Pena, Noel
core +1 more source
Advanced Healthcare Materials, EarlyView.Synthetic matrix metalloproteinase (MMP)‐degradable polyethylene glycol (PEG)‐based hydrogels are developed to investigate the influence of mechanical and biochemical cues on cardioid development. Matrix stiffness and cell adhesion motifs significantly regulate cardioid formation, chamber morphogenesis, contractile function, and cardioid transcriptome.
Yuanhui Song +6 more
wiley +1 more source