K562 Chronic Myeloid Leukemia Cells as a Dual β3-Expressing Functional Cell Line Model to Investigate the Effects of Combined αIIbβ3 and αvβ3 Antagonism. [PDF]
Elsharif AA+3 more
europepmc +1 more source
“Inside-out” signal transduction inhibited by isolated integrin cytoplasmic domains
Y.P. Chen+7 more
openalex +1 more source
Immunolocalization of integrin receptors in normal lymphoid tissues [PDF]
MM Zutter
openalex +1 more source
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang+3 more
wiley +1 more source
In Silico Prediction of Tetrastatin-Derived Peptide Interactions with αvβ3 and α5β1 Integrins. [PDF]
Paturel V+3 more
europepmc +1 more source
Regulated Ca2+ signalling through leukocyte CD11b/CD18 integrin [PDF]
Dario C. Altieri+2 more
openalex +1 more source
Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu+16 more
wiley +1 more source
Anoikis resistance in gastric cancer: a comprehensive review. [PDF]
D'Amore T+10 more
europepmc +1 more source
De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang+25 more
wiley +1 more source
Mammalian cells measure the extracellular matrix area and respond through switching the adhesion state. [PDF]
Wang X+8 more
europepmc +1 more source