Results 161 to 170 of about 221,644 (354)

Conformational Changes in the Integrin औA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement [PDF]

, 2003
A. Paul Mould, Stephanie Barton, Janet A. Askari, Paul McEwan, Patrick A. Buckley, Susan E. Craig, Martin J. Humphries   +6 more
openalex   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Polyomavirus Enhancer-binding Protein 2/Core Binding Factor/Acute Myeloid Leukemia Factors Contribute to the Cell Type-specific Activity of the CD11a Integrin Gene Promoter [PDF]

, 2000
Amaya Puig‐Kröger, Cristina López-Rodrı́guez, Miguel Relloso, Tilman Sánchez-Elsner, Arsenio Nueda, Eduardo Muñóz, Carmelo Bernabéu, Ángel L. Corbí   +7 more
openalex   +1 more source

The synergistic mechanism of fibroblast growth factor 18 and integrin β1 in rat abdominal aortic aneurysm repair [PDF]

, 2022
Yilong Guo, Wei Ren, Yuan He, Hongpeng Zhang, Jianqing Deng, Wei Guo   +5 more
openalex   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Loss of Cardiomyocyte Integrin-Linked Kinase Produces an Arrhythmogenic Cardiomyopathy in Mice [PDF]

, 2015
Khaï Le Quang, Ange Maguy, Xiaoyan Qi, Patrice Naud, Feng Xiong, Artavazd Tadevosyan, Yanfen Shi, Denis Chartier, Jean‐Claude Tardif, Dobromir Dobrev, Stanley Nattel   +10 more
openalex   +1 more source

Integrins as Drug Targets: Is There a Future?

, 2021
Dermot Cox
openalex   +2 more sources

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Association between integrin‑linked kinase and hyperthermia in oral squamous cell carcinoma

, 2017
Jun Zhao, Na Liu, Xinhe Hao, Lin Que, Jiyuan Liu, Xiufa Tang   +5 more
openalex   +2 more sources

Modulation of Cancer-Associated Fibrotic Stroma by An Integrin αvβ3 Targeting Protein for Pancreatic Cancer Treatment

, 2020
Ravi Chakra Turaga, Malvika Sharma, Falguni Mishra, Alyssa M. Krasinskas, Yi Yuan, Jenny J. Yang, Shiyuan Wang, Chun‐Feng Liu, Li Sun, Zhi‐Ren Liu   +9 more
openalex   +1 more source