Results 1 to 10 of about 3,672,063 (202)
Scientific integrity from a meta-ethical perspective: more contextualization and research ethics committees? A preliminary meta-ethics study [PDF]
BMC Research NotesObjective We aimed to begin studying, more empirically, within our ethics department,scientific integrity itself, considering scientific integrity as an integral part of morality.
Henri-Corto Stoeklé +2 more
doaj +2 more sources
Distinct Motifs in ATAD5 C-Terminal Domain Modulate PCNA Unloading Process
Cells, 2022 Proliferating cell nuclear antigen (PCNA) is a DNA clamp that functions in key roles for DNA replication and repair. After the completion of DNA synthesis, PCNA should be unloaded from DNA in a timely way.
Eunjin Ryu +5 more
doaj +1 more source
CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway
Nature Communications, 2022 RNA has been implicated in DNA repair. This work shows that the interplay of RNAPII-generated nascent RNA, RNA:DNA hybrids and the resection factor CtIP guide DNA double strand break repair pathway choice towards error-free homologous recombination.
Daniel Gómez-Cabello +4 more
doaj +1 more source
You-qi chuyun, 2020 To solve the problems of insufficient power, high speed impact, high energy consumption, etc. of the detectors applied to large-diameter pipelines before the conventional cup-type pipelines are put into production, the self-driven inner detector suitable
Jianfeng ZHENG +6 more
doaj +1 more source
Scientific Reports, 2021 Proliferating cell nuclear antigen (PCNA) plays a critical role as a processivity clamp for eukaryotic DNA polymerases and a binding platform for many DNA replication and repair proteins.
Su Hyung Park +3 more
doaj +1 more source
CTCF is a barrier for 2C-like reprogramming
Nature Communications, 2021 Embryos at the 2-cell (2C) stage are totipotent, and overexpression of Dux transcription factor convert embryonic stem cells (ESCs) to a 2C-like state.
Teresa Olbrich +16 more
doaj +1 more source
DRAGen – A deep learning supported RVE generator framework for complex microstructure models
Heliyon, 2023 In this study an improved version of the Discrete RVE Automation and Generation Framework, also called DRAGen, is presented. The Framework incorporates a generator for Representative Volume Elements (RVEs).
Manuel Henrich +8 more
doaj +1 more source
Numerical analysis of hydrogen-assisted rolling-contact fatigue of wind turbine bearings [PDF]
Fracture and Structural Integrity, 2014 Offshore wind parks at locations further from the shore often involve serious difficulties, e.g. the maintenance. The bearings of offshore wind turbines are prone to suffer hydrogen-assisted rolling-contact fatigue (HA-RCF).
J. Toribio +3 more
doaj +3 more sources
Construction of full life cycle integrity management system for oil and gas pipelines
You-qi chuyun, 2020 In order to strengthen the risk prevention and control of oil and gas pipelines, the integrity management concept is introduced into the Chinese pipeline industry.
Pengchao CHEN +2 more
doaj +1 more source
Crystals, 2022 Dual-phase high-strength titanium alloy has the properties of high specific strength and good toughness, which have resulted in its gradual use in the fields of oil and gas well engineering.
Wenlan Wei +5 more
doaj +1 more source