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On the taxonomy and functions of integrons
2022Integrons are genetic elements that helped precipitate the global antimicrobial resistance crisis. However, the role that integrons have played in the resistance crisis is just a specialised case of their more general role in microbial evolution. Their ability to capture a diverse range of gene cassettes means that they can drive rapid adaptation to ...
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[Structure and function of integrons].
Enfermedades infecciosas y microbiologia clinica, 2002Integrons are genetic elements known for their role in the acquisition and expression of genes conferring antibiotic resistance. Integrons have an integrase gene (intI), an attachment site (attI), into which individual resistance genes are inserted and a promotor sequence (Pant), allowing expression of resistance genes (cassette-associated genes ...
Montserrat, Sabaté, Guillem, Prats
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Transcription of integron‐harboured gene cassette impacts integration efficiency in class 1 integron
Molecular Microbiology, 2011SummaryClass 1 integrons play important roles in the dissemination of antibiotic resistance genes among bacteria. Generally, class 1 integron consists of an integrase gene (intI1), a recombination site (attI1) and a promoter (Pc) that drives the transcription of the downstreamed gene cassettes.
Quhao, Wei +6 more
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Integron and antibiotic resistance
Pathology, 2009Since the advent of antibiotic chemotherapy, the spread of drug resistance genes among clinical isolates of bacteria has become an ever-increasing problem. The increase in drug resistance has been facilitated by the association of antibiotic resistance genes with a variety of mobile genetic elements including plasmids, transposons, integrons and gene ...
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2018
Integrons are genetic recombination platforms that enhance bacterial evolvability by enabling the acquisition and differential expression of new genes. These genes are embedded in mobile elements, named cassettes, which can be stockpiled to form a long array of adaptive functions whose expression is driven by the Pc promoter within the integron ...
José Antonio Escudero +2 more
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Integrons are genetic recombination platforms that enhance bacterial evolvability by enabling the acquisition and differential expression of new genes. These genes are embedded in mobile elements, named cassettes, which can be stockpiled to form a long array of adaptive functions whose expression is driven by the Pc promoter within the integron ...
José Antonio Escudero +2 more
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Integrons and integron-related antibiotic resistance in acinetobacter
2017Acinetobacter baumannii is responsible for an increasing number of nosocomial infections in patients receiving intensive care and comprehensive antibiotic resistance of these organisms hampers treatment of infections due to A.baumannii. The molecular basis of antibiotic resistance in A.baumannii has not been extensively investigated. A few studies have
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Class 1 integron causes vulnerability to formaldehyde in Escherichia coli
Archives of Microbiology, 2021Mehran Ghaemi +2 more
exaly

