Results 11 to 20 of about 24,855 (253)
Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution [PDF]
The ISME Journal, 2014 Around all human activity, there are zones of pollution with pesticides, heavy metals, pharmaceuticals, personal care products and the microorganisms associated with human waste streams and agriculture.
M. Gillings +5 more
semanticscholar +2 more sources
[Integrons: gene collectors]. [PDF]
Revista Argentina de microbiologia, 2010 Integrons gained great interest due to their participation in resistance gene recruitment and expression. Their basic structure includes a fragment that encodes an integrase (intI) followed by a recognition sequence (attI) into which they may incorporate gene cassettes (encoding resistance mechanisms). A promoter (Pc) embedded within the integrase gene
J A, Di Conza, G O, Gutkind
openaire +3 more sources
The Natural History of Integrons [PDF]
Microorganisms, 2021 Integrons were first identified because of their central role in assembling and disseminating antibiotic resistance genes in commensal and pathogenic bacteria. However, these clinically relevant integrons represent only a small proportion of integron diversity.
Timothy M. Ghaly +5 more
openaire +4 more sources
Activation of class 1 integron integrase is promoted in the intestinal environment
PLoS Genetics, 2022 Class 1 integrons are widespread genetic elements playing a major role in the dissemination of antibiotic resistance. They allow bacteria to capture, express and exchange antibiotic resistance genes embedded within gene cassettes.
Murielle Baltazar +7 more
semanticscholar +1 more source
Resistance integrons and super-integrons [PDF]
Clinical Microbiology and Infection, 2004 Integrons are genetic elements composed of a gene encoding an integrase, gene cassettes and an integration site for the gene cassettes (att). The integrase excises and integrates the gene cassettes from and into the integron, but integrons themselves are not mobile. Two groups of integrons are known: resistance integrons and super-integrons. Nearly all
Fluit, A.C., Schmitz, F.-J.
openaire +2 more sources
Water Research, 2021 Highlights • Prevalence and types of integrons vary widely across a wastewater network.• Human-impacted class 1 integrons carrying ARGs dominate, but are highest in hospital wastewater.• New qPCR assays are reported that segregate "anthropogenic" class 1
M. Quintela-Baluja +6 more
semanticscholar +1 more source
Study on multidrug resistance related genes of Salmonella isolated from food and clinical samples
Zhongguo shipin weisheng zazhi, 2023 ObjectiveTo investigate distribution of integron and extended-spectrum β-lactamase produced by Salmonella isolated from food and clinical samples， and explore the relationship between different drug resistance genes and multidrug resistance ...
ZHANG Mingyan +3 more
doaj +1 more source
Communications Biology, 2021 Integrons are bacterial genetic elements that can capture mobile gene cassettes. They are mostly known for their role in the spread of antibiotic resistance cassettes, contributing significantly to the global resistance crisis. These resistance cassettes
Timothy M. Ghaly, S. Tetu, M. Gillings
semanticscholar +1 more source
Prevalence of Antibiotic Resistome in Ready-to-Eat Salad [PDF]
, 2020 Ready-to-eat salad harbors microorganisms that may carry various antibiotic resistance genes (ARGs). However, few studies have focused on the prevalence of ARGs on salad, thus underestimating the risk of ARGs transferring from salad to consumers. In this
Giles, Madeline +7 more
core +2 more sources