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Profile and resistance levels of 136 integron resistance genes
, 2023 Integrons have played a major role in the rise and spread of multidrug resistance in Gram-negative pathogens and are nowadays commonplace among clinical isolates.
Vergara, Ester +4 more
core +1 more source
The evolutionary history of chromosomal super-integrons provides an ancestry for multiresistant integrons [PDF]
Proceedings of the National Academy of Sciences, 2001 Integrons are genetic elements that acquire and exchange exogenous DNA, known as gene cassettes, by a site-specific recombination mechanism. Characterized gene cassettes consist of a target recombination sequence ( attC site) usually associated with a single open reading frame coding for an antibiotic resistance
D A, Rowe-Magnus +5 more
openaire +2 more sources
Medical Journal of Babylon, 2023 Background: Clinical management of bacterial infections has faced significant difficulties in recent years due to the advent and spread of multiple drug-resistant (MDR) bacteria.
Ahmed Abdulkareem Almuttairi +1 more
doaj +1 more source
Regulatory control of integron-mediated antibacterial resistance [PDF]
, 2017 Bacterial infections rendered almost untreatable by resistance to last-line antibiotics such as carbapenems are now a common occurrence worldwide. Genes conferring carbapenem resistance are commonly associated with structures called integrons, but little
McAlister, Erin Victoria
core +1 more source
Mobile Genetic Elements, 2012 Integrons are genetic elements first described at the end of the 1980s. Although most integrons were initially described in human clinical isolates, they have now been identified in many non-clinical environments, such as water and soil. Integrons are present in ≈10% of the sequenced bacterial genomes and are frequently linked to mobile genetic ...
Domingues, Sara +2 more
openaire +2 more sources
, 2020 Salmonella infection is the second most common cause of diarrhea in Thailand; however, the data on antimicrobial resistance is limited. There were137 Salmonella strains, isolated from patients and 126 strains isolated from chicken meat, collected from ...
Phanita Chankate +3 more
core +1 more source
Journal of Pure and Applied Microbiology, 2023 Antimicrobial agents are widely used for treatment of animal and human diseases. Heavy use of antimicrobial agents permits bacteria to develop resistance to these agents specifically when a dose of antibiotic is insufficient or course of treatment is ...
Yathrib Al-Ubaidy, Amjed Alsultan
doaj +1 more source
Frontiers in Microbiology, 2023 Bacteriophages are versatile mobile genetic elements that play key roles in driving the evolution of their bacterial hosts through horizontal gene transfer. Phages co-evolve with their bacterial hosts and have plastic genomes with extensive mosaicism. In
Qin Qi +7 more
doaj +1 more source
Characterization of the novel In1059 harbouring VIM gene cassette
Antimicrobial Resistance and Infection Control, 2017 Background VIM-type enzyme encodes the most widely acquired metallo-β-lactamases in Gram- negative bacteria. To obtain current epidemiological data for integrons from enterobacteriae in hospital, the study characterizes the genetic structure in In1059 by
Dongguo Wang +6 more
doaj +1 more source