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The Natural History of Integrons [PDF]
Microorganisms, 2021 Integrons were first identified because of their central role in assembling and disseminating antibiotic resistance genes in commensal and pathogenic bacteria. However, these clinically relevant integrons represent only a small proportion of integron diversity.
Timothy M. Ghaly +5 more
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Resistance integrons and super-integrons [PDF]
Clinical Microbiology and Infection, 2004 Integrons are genetic elements composed of a gene encoding an integrase, gene cassettes and an integration site for the gene cassettes (att). The integrase excises and integrates the gene cassettes from and into the integron, but integrons themselves are not mobile. Two groups of integrons are known: resistance integrons and super-integrons. Nearly all
Fluit, A.C., Schmitz, F.-J.
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Resistance integrons: class 1, 2 and 3 integrons [PDF]
Annals of Clinical Microbiology and Antimicrobials, 2015 As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and ...
Deng, Yang +9 more
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Evolution of class 1 integrons: Mobilization and dispersal via food-borne bacteria. [PDF]
PLoS ONE, 2017 Class 1 integrons have played a major role in the global dissemination of antibiotic resistance. Reconstructing the history of class 1 integrons might help us control further spread of antibiotic resistance by understanding how human activities influence
Timothy M Ghaly +4 more
doaj +1 more source
Abundance of Class 1 Integron-Integrase and Sulfonamide Resistance Genes in River Water and Sediment Is Affected by Anthropogenic Pressure and Environmental Factors [PDF]
Microbial Ecology, 2016 Ryszard Koczura +2 more
exaly +2 more sources
Prevalence of integron classes in Gram-negative clinical isolated bacteria in Iran: a systematic review and meta-analysis [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Integrons, as a potential element in the distribution and maintenance of drug resistance, have thoroughly been established. It is known that the high prevalence of integrons in multidrug-resistant (MDR) clinical isolates has become a ...
Ali Pormohammad +3 more
doaj +1 more source
Transcription of integron‐harboured gene cassette impacts integration efficiency in class 1 integron [PDF]
Molecular Microbiology, 2011 SummaryClass 1 integrons play important roles in the dissemination of antibiotic resistance genes among bacteria. Generally, class 1 integron consists of an integrase gene (intI1), a recombination site (attI1) and a promoter (Pc) that drives the transcription of the downstreamed gene cassettes.
Quhao Wei +6 more
openalex +3 more sources
Biotropia: The Southeast Asian Journal of Tropical Biology, 2011 The genotype of antibiotic resistance in natural isolates of Escherichia coli was determined through integron detection and characterization of the associated antibiotic resistance. E.
ESTI PUSPITASARI +3 more
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Frontiers in Microbiology, 2022 Salmonella enterica serovar Indiana (S. Indiana) has aroused widespread concern as an important zoonotic pathogen. The molecular mechanism of multidrug resistance (MDR) in S. Indiana is not known and should be assessed.
Xuefeng Wang +6 more
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