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The Integron: Adaptation On Demand.
Microbiology Spectrum, 2015 International audienceThe integron is a powerful system which, by capturing, stockpiling, and rearranging new functions carried by gene encoding cassettes, confers upon bacteria a rapid adaptation capability in changing environments.
Loot, Céline +3 more
core +4 more sources
Integron prevalence and diversity in manured soil [PDF]
Applied and Environmental Microbiology, 2010 Integron abundance and diversity were studied in soil amended with pig slurry. Real-time PCR illustrated a significant increase in class 1 integron prevalence post slurry-application with increased prevalence still evident at 10 months post-application ...
K. G. Byrne-Bailey +20 more
core +4 more sources
Integron diversity in heavy-metal-contaminated mine tailings and inferences about integron evolution [PDF]
Applied and Environmental Microbiology, 2004 Integrons are horizontal gene transfer (HGT) systems containing elements necessary for site-specific re-combination and expression of foreign DNA. The overall phylogenetic distribution of integrons and range of genes that can be transferred by integrons ...
D. R. Nemergut +2 more
core +3 more sources
The Natural History of Integrons [PDF]
Microorganisms, 2021 Integrons were first identified because of their central role in assembling and disseminating antibiotic resistance genes in commensal and pathogenic bacteria. However, these clinically relevant integrons represent only a small proportion of integron diversity.
Timothy M. Ghaly +5 more
openaire +4 more sources
Resistance integrons and super-integrons [PDF]
Clinical Microbiology and Infection, 2004 Integrons are genetic elements composed of a gene encoding an integrase, gene cassettes and an integration site for the gene cassettes (att). The integrase excises and integrates the gene cassettes from and into the integron, but integrons themselves are not mobile. Two groups of integrons are known: resistance integrons and super-integrons. Nearly all
Fluit, A.C., Schmitz, F.-J.
openaire +2 more sources
Prevalence of integron classes in Gram-negative clinical isolated bacteria in Iran: a systematic review and meta-analysis [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Integrons, as a potential element in the distribution and maintenance of drug resistance, have thoroughly been established. It is known that the high prevalence of integrons in multidrug-resistant (MDR) clinical isolates has become a ...
Ali Pormohammad +3 more
doaj +1 more source
Resistance integrons: class 1, 2 and 3 integrons [PDF]
Annals of Clinical Microbiology and Antimicrobials, 2015 As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and ...
Deng, Yang +9 more
openaire +2 more sources
Frontiers in Microbiology, 2022 Salmonella enterica serovar Indiana (S. Indiana) has aroused widespread concern as an important zoonotic pathogen. The molecular mechanism of multidrug resistance (MDR) in S. Indiana is not known and should be assessed.
Xuefeng Wang +6 more
doaj +1 more source
Mobile DNA, 2011 Background Integrons are found in hundreds of environmental bacterial species, but are mainly known as the agents responsible for the capture and spread of antibiotic-resistance determinants between Gram-negative pathogens.
Cambray Guillaume +9 more
doaj +1 more source
Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation [PDF]
, 2016 International audienceTyrosine (Y)-recombinases have evolved to deliver mechanistically different reactions on a variety of substrates, but these evolutionary transitions are poorly understood.
Escudero, Jose Antonio +6 more
core +1 more source