Cassette recruitment in the chromosomal Integron of Vibrio cholerae [PDF]
International audienceIntegrons are genetic systems conferring to bacteria a rapid adaptation capability. The integron integrase is able to capture, stockpile and shuffle novel functions embedded in cassettes.
Fournes, Florian +8 more
core +1 more source
Impact of Wastewater Treatment on the Prevalence of Integrons and the Genetic Diversity of Integron Gene Cassettes [PDF]
ABSTRACTThe integron platform allows the acquisition, expression, and dissemination of antibiotic resistance genes within gene cassettes. Wastewater treatment plants (WWTPs) contain abundant resistance genes; however, knowledge about the impacts of wastewater treatment on integrons and their gene cassettes is limited.
Xin-Li, An +5 more
openaire +2 more sources
Class 1 integrons facilitate horizontal gene transfer, significantly influencing antibiotic resistance gene (ARG) dissemination within microbial communities.
Yan Zhang +5 more
doaj +1 more source
Investigating Antibiotic Resistance Pattern and Prevalence of Class I, II, III Integron Genes in K. Pneumoniae Isolated from Clinical Samples in Sahrekord, Iran [PDF]
Background & Objective: Acquiring integron is an important factor in multidrug resistance in the intestinal gram negative microorganisms. The most common integron cassette contains the genes associated with resistance to a wide range of antimicrobial ...
Marzeyeh Soleymanian +2 more
doaj
BEL-1, a novel clavulanic acid-inhibited extended-spectrum ß-lactamase, and the class 1 integron In120 in Pseudomonas aeruginosa [PDF]
Screening by a double-disk synergy test identified a Pseudomonas aeruginosa isolate that produced a clavulanic acid-inhibited expanded-spectrum β-lactamase (ESBL).
Nordmann, P. +4 more
core +1 more source
Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen with an increase in the frequency of infections caused by multidrug resistant (MDR) and extensively drug resistant (XDR) strains, limiting the available therapeutic options.
Ana M. Rada +9 more
doaj +1 more source
A study of clinical strains of Pseudomonas Aeruginosa and the investigation of antibiotic resistance mechanisms in the multidrug resistant strain PA13 [PDF]
Thirteen clinical strains of bacteria from two Irish hospitals were identified as Pseudomonas aeruginosa using classical methods, API 20NE and Biolog GN. Their identification was confirmed by 16S rRNA gene sequencing.
Ferguson, Damien
core
Integron Content in Select Study Isolates.
Integron PCR gene products of WC 13–24 are shown. The block arrow marks the 550 base pair PCR product of the prevalent strain A. baumannii. The water control is labeled “neg.” The cartoon shows the layout of a typical Class I integron.
Audrey N. Schuetz (337592) +8 more
core +1 more source
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali +10 more
wiley +1 more source
Importance of integrons in the diffusion of resistance [PDF]
Horizontal transfer of resistance genes is a successful mechanism for the transmission and dissemination of multiple drug resistance among bacterial pathogens. The impact of horizontally transmitted genetic determinants in the evolution of resistance is particularly evident when resistance genes are physically associated in clusters and transferred en ...
openaire +3 more sources

