Results 41 to 50 of about 20,212 (269)

The evolutionary history of chromosomal super-integrons provides an ancestry for multiresistant integrons [PDF]

Proceedings of the National Academy of Sciences, 2001
Integrons are genetic elements that acquire and exchange exogenous DNA, known as gene cassettes, by a site-specific recombination mechanism. Characterized gene cassettes consist of a target recombination sequence ( attC site) usually associated with a single open reading frame coding for an antibiotic resistance
D A, Rowe-Magnus, A M, Guerout, P, Ploncard, B, Dychinco, J, Davies, D, Mazel   +5 more
openaire   +2 more sources

Correlation between class 1 integron of Escherichia coli and multidrug resistance in lower respiratory tract infection

Journal of Infection in Developing Countries, 2017
Introduction: Class 1 integrons are mobile genetic elements considered to be responsible for the transfer of multidrug resistance. This study aimed to investigate the distribution of type 1 integrons in multidrug-resistantEscherichiacolifrom hospital ...
Yu Wang, Bingbing Kong, Wenping Yang, Xin Zhao   +3 more
doaj   +1 more source

IntegronFinder 2.0: Identification and Analysis of Integrons across Bacteria, with a Focus on Antibiotic Resistance in Klebsiella

Microorganisms, 2022
Integrons are flexible gene-exchanging platforms that contain multiple cassettes encoding accessory genes whose order is shuffled by a specific integrase.
Bertrand Néron, Eloi Littner, Matthieu Haudiquet, Amandine Perrin, Jean Cury, Eduardo P. C. Rocha   +5 more
doaj   +1 more source

Integron Diversity in Heavy-Metal-Contaminated Mine Tailings and Inferences about Integron Evolution [PDF]

Applied and Environmental Microbiology, 2004
ABSTRACTIntegrons are horizontal gene transfer (HGT) systems containing elements necessary for site-specific recombination and expression of foreign DNA. The overall phylogenetic distribution of integrons and range of genes that can be transferred by integrons are unknown.
D R, Nemergut, A P, Martin, S K, Schmidt
openaire   +2 more sources

Investigating Antibiotic Resistance Pattern and Prevalence of Class I, II, III Integron Genes in K. Pneumoniae Isolated from Clinical Samples in Sahrekord, Iran [PDF]

Journal of Advanced Biomedical Sciences, 2018
Background & Objective: Acquiring integron is an important factor in multidrug resistance in the intestinal gram negative microorganisms. The most common integron cassette contains the genes associated with resistance to a wide range of antimicrobial ...
Marzeyeh Soleymanian, Elahe Tajbakhsh, Zahra Bam zadeh   +2 more
doaj  

Complete sequence of the IncA/C 1 plasmid pCf587 carrying bla PER-2 from citrobacter freundii [PDF]

, 2018
The bla PER-2 -harboring plasmid pCf587 (191,541 bp) belongs to lineage IncA/C 1 and is closely related to pRA1. It contains a large resistance island including the bla PER-2 gene between two copies of ISKox2-like elements, the toxin-antitoxin module ...
Dabos, Laura, Girlich, Delphine, Gutkind, Gabriel Osvaldo, Naas, Thierry, Power, Pablo, Ruggiero, Melina   +5 more
core   +1 more source

Integrons: Past, Present, and Future [PDF]

Microbiology and Molecular Biology Reviews, 2014
SUMMARY Integrons are versatile gene acquisition systems commonly found in bacterial genomes. They are ancient elements that are a hot spot for genomic complexity, generating phenotypic diversity and shaping adaptive responses. In recent times, they have had a major role in the acquisition, expression, and dissemination of antibiotic ...
openaire   +2 more sources

Integrons [PDF]

Mobile Genetic Elements, 2012
Integrons are genetic elements first described at the end of the 1980s. Although most integrons were initially described in human clinical isolates, they have now been identified in many non-clinical environments, such as water and soil. Integrons are present in ≈10% of the sequenced bacterial genomes and are frequently linked to mobile genetic ...
Domingues, Sara, da Silva, Gabriela J., Nielsen, Kaare M.   +2 more
openaire   +2 more sources

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Integron-Mediated Antimicrobial Resistance and Virulence Factors in Salmonella Typhimurium Isolated from Poultry

Animals
This study investigates antimicrobial-resistant (AMR) Salmonella Typhimurium in poultry, focusing on how class I integrons contribute to AMR and virulence. Using whole genome sequencing, researchers analyzed 26 S. Typhimurium isolates from U.S.
Elizabeth Kim, Nora Jean Nealon, Katherine A. Murray, Cydney Jardine, Roberta Magnuson, Sangeeta Rao   +5 more
doaj   +1 more source