Results 61 to 70 of about 8,780 (184)

Biological Systems as Physical Data Processors: Evolution as a Case of Embodied Computing

open access: yesBioEssays, Volume 48, Issue 10, October 2026.
Embodied biological computing is process through which biological systems gravitate toward attractors in a solution space through a thermodynamically favored process of information capture. Applications in biotechnology, in particular metabolic engineering are numerous.
Víctor de Lorenzo
wiley   +1 more source

Shuffling of DNA Cassettes in a Synthetic Integron [PDF]

open access: yes, 2013
The complexity of even small gene networks makes them hardly amenable to rational design. Testing random combinations of genetic elements in a directed evolution procedure is thus of interest for many applications including metabolic engineering. Here we describe how the recombination machinery of class 1 integrons can be used to deliver and shuffle ...
Bikard, David, Mazel, Didier
openaire   +3 more sources

Molecular Characterization of Integrons in Acinetobacter baumannii : Description of a Hybrid Class 2 Integron [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2000
ABSTRACT Twenty Acinetobacter baumannii strains resistant to various antibiotics were analyzed for integron content and sequences of the amplification products. Sixteen clinical isolates had a class 1 integron, 2 contained an additional class 1 or class 2 integron, but no class 3 integron was detected ...
M C, Ploy   +3 more
openaire   +2 more sources

Antimicrobial resistance and integrons of ESBL-producing thermotolerant coliforms from a water reservoir in Tai'an, China

open access: yesJournal of Infection in Developing Countries, 2017
Introduction: The contamination of water environments by extended-spectrum β-lactamases-producing thermotolerant coliforms (ESBL-TC) has aroused public concern.
Hongna Zhang   +5 more
doaj   +1 more source

Comparative Genomic Analysis of Multidrug‐Resistant Escherichia coli Across Poultry–Human–Environmental Interfaces

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Whole‐genome sequencing analysis of Escherichia coli isolates from broiler, layer and sonali chickens in Bangladesh shown extensive antimicrobial resistance, diverse virulence factors, plasmid‐mediated resistance, and a highly open pangenome. Comparative genomic analyses demonstrated close genetic relationships with global strains, highlighting the One
Md. Rokibul Hasan Shanto   +6 more
wiley   +1 more source

Antimicrobial profile of Salmonella enterica serotype Choleraesuis from free-range swine in Kakamega fish market, western Kenya

open access: yesJournal of Infection in Developing Countries, 2014
Introduction: Salmonella enterica subspecies enterica serovar Choleraesuis is a host-adapted, facultative, intracellular pathogen that causes swine paratyphoid. Its antimicrobial resistance presents a challenge to feed manufacturing industries.
David M Onyango   +4 more
doaj   +1 more source

Genomic Detection of Multidrug‐Resistant H58 ST1 Salmonella Typhi in a South African Urban Waterway Reveals Epidemiological Links With Clinical Isolates

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Genomic analysis of four S. Typhi from a South African urban river uncovered two multidrug‐resistant H58 strains carrying qacEΔ1, revealing strong phylogenetic links to clinical isolates and underscoring urban rivers as potential transmission pathways. ABSTRACT Typhoid fever remains a major public health concern in South Africa.
Sanelisiwe Thinasonke Duze   +2 more
wiley   +1 more source

An evaluation of clonal relationship by PFGE method in Acinetobacter baumannii isolates, examining integron presence and antibiotic resistance

open access: yesJournal of Infection in Developing Countries
Introduction: This study aims to investigate the presence of class 1, 2, and 3 integrons in Acinetobacter baumannii isolates, evaluate the relationship between integrons and antibiotic resistance and determine the clonal relationship between isolates by
Sedef Zeliha Öner   +5 more
doaj   +1 more source

Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions

open access: yeseLife, 2020
Molecular examples of evolutionary innovation are scarce and generally involve point mutations. Innovation can occur through larger rearrangements, but here experimental data is extremely limited.
José Antonio Escudero   +5 more
doaj   +1 more source

Iran's Escherichia coli AMR Landscape (2010–2025): A One Health Systematic Review and Meta‐Analysis

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
This One Health systematic review and meta‐analysis of 368 studies (2010–2025) reveals that 47.2% of E. coli isolates in Iran are ESBL‐producers, with alarming resistance to penicillins, cephalosporins, and fluoroquinolones. Critically, resistance to last‐resort antibiotics—colistin and ertapenem—is significantly increasing over time.
Arezoo Dehghan   +9 more
wiley   +1 more source

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