Results 71 to 80 of about 8,633 (182)

Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions

open access: yeseLife, 2020
Molecular examples of evolutionary innovation are scarce and generally involve point mutations. Innovation can occur through larger rearrangements, but here experimental data is extremely limited.
José Antonio Escudero   +5 more
doaj   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 8, Page 1478-1491, August 2026.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos   +11 more
wiley   +1 more source

Impacts of anthropogenic activity on the ecology of class 1 integrons and integron-associated genes in the environment [PDF]

open access: yesThe ISME Journal, 2011
Abstract The impact of human activity on the selection for antibiotic resistance in the environment is largely unknown, although considerable amounts of antibiotics are introduced through domestic wastewater and farm animal waste. Selection for resistance may occur by exposure to antibiotic residues or by co-selection for mobile genetic ...
William H, Gaze   +10 more
openaire   +2 more sources

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury   +3 more
wiley   +1 more source

Integron Diversity in Heavy-Metal-Contaminated Mine Tailings and Inferences about Integron Evolution [PDF]

open access: yesApplied and Environmental Microbiology, 2004
ABSTRACTIntegrons are horizontal gene transfer (HGT) systems containing elements necessary for site-specific recombination and expression of foreign DNA. The overall phylogenetic distribution of integrons and range of genes that can be transferred by integrons are unknown.
D R, Nemergut, A P, Martin, S K, Schmidt
openaire   +2 more sources

Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems

open access: yesMicrobial Biotechnology, Volume 19, Issue 8, August 2026.
Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley   +1 more source

Origin of the Mobile Di-Hydro-Pteroate Synthase Gene Determining Sulfonamide Resistance in Clinical Isolates

open access: yesFrontiers in Microbiology, 2019
Sulfonamides are synthetic chemotherapeutic agents that work as competitive inhibitors of the di-hydro-pteroate synthase (DHPS) enzyme, encoded by the folP gene.
Miquel Sánchez-Osuna   +3 more
doaj   +1 more source

Molecular Detection of Multidrug Resistant Salmonella Species Isolated from Broiler Farm in Bangladesh

open access: yesPathogens, 2020
Multidrug resistant (MDR) Salmonella are a leading cause of foodborne diseases and serious human health concerns worldwide. In this study we detected MDR Salmonella in broiler chicken along with the resistance genes and class 1 integron gene intl1.
Shanzida Binte Alam   +9 more
doaj   +1 more source

Global Distribution and Comparative Resistance Profiles of Escherichia coli Isolated From Bovine Meat and Meat Products: Evidence From Network Meta‐Analysis

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Schematic overview of the study and its principal findings. E. coli isolated from bovine meat and meat products was evaluated for antimicrobial resistance using Bayesian network meta‐analysis. The graphical abstract highlights the antimicrobial resistance ranking based on SUCRA, showing high resistance to penicillin, doxycycline, amoxicillin ...
Yaser Khorram Del   +5 more
wiley   +1 more source

Molecular analysis of Shiga toxin-producing Escherichia coli O157:H7 and non-O157 strains isolated from calves

open access: yesOnderstepoort Journal of Veterinary Research, 2018
Shiga toxin-producing Escherichia coli (STEC) O157 and non-O157 are food-borne pathogens and contaminants of foods of animal origin. This study was conducted to investigate the presence of virulence and integrase genes in STEC isolates from diarrhoeic ...
Maryam Kohansal, Ali Ghanbari Asad
doaj   +1 more source

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