Results 71 to 80 of about 8,780 (184)

Impacts of anthropogenic activity on the ecology of class 1 integrons and integron-associated genes in the environment [PDF]

The ISME Journal, 2011
Abstract The impact of human activity on the selection for antibiotic resistance in the environment is largely unknown, although considerable amounts of antibiotics are introduced through domestic wastewater and farm animal waste. Selection for resistance may occur by exposure to antibiotic residues or by co-selection for mobile genetic ...
William H, Gaze, Lihong, Zhang, Nouradin A, Abdouslam, Peter M, Hawkey, Leo, Calvo-Bado, Jeremy, Royle, Helen, Brown, Susan, Davis, Paul, Kay, Alistair B A, Boxall, Elizabeth M H, Wellington   +10 more
openaire   +2 more sources

First Report of blaCTX‐M‐15 in a Marine Thermotolerant Enterobacter Isolate From Bangladesh: Genomic Insights Into Halotolerance and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Marine‐derived Enterobacter kobei, exhibiting thermotolerance and salt tolerance, is ESBL‐producing and harbors AMR genes (blaCTX‐M‐15, qnrS1) and mobile genetic elements, indicating environmental spread of antimicrobial resistance. ABSTRACT Marine ecosystems are becoming important reservoirs for antimicrobial resistance (AMR). However, genomic data on
Md. Arifur Rahman, Rafid Muntasir Ul Azam, Md. Sazib Hossain, Samina Momtaz, Anowara Begum, Munawar Sultana   +5 more
wiley   +1 more source

Metagenomic Characterisation of Antibiotic Resistance in Anaerobic Digesters and Their Implications for Environmental Health

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Anaerobic digester metagenomes revealed diverse resistance‐associated annotations and antibiotic target loci, highlighting their potential role in environmental AMR surveillance. The findings emphasise the need for cautious interpretation of resistome profiles and further host‐resolved analyses to determine the mobility and clinical relevance of ...
Olasunbo Aina Olasupo, Oluwaseyi Paul Olaniyan, Sunday Babatunde Akinde, Ademola Ayodele Adesoye, Fatimah Adenike Ajadi, Omokaro Obire, Elijah Kolawole Oladipo, Waidi Folorunso Sule, Olamilekan Emmanuel Oyinloye, Adedolapo Aishat Salami, Emmanuel Sunday Fajoyegbe, Adejoke Janet Ajani, Olabisi Ojo   +12 more
wiley   +1 more source

Origin of the Mobile Di-Hydro-Pteroate Synthase Gene Determining Sulfonamide Resistance in Clinical Isolates

Frontiers in Microbiology, 2019
Sulfonamides are synthetic chemotherapeutic agents that work as competitive inhibitors of the di-hydro-pteroate synthase (DHPS) enzyme, encoded by the folP gene.
Miquel Sánchez-Osuna, Pilar Cortés, Jordi Barbé, Ivan Erill   +3 more
doaj   +1 more source

Molecular Detection of Multidrug Resistant Salmonella Species Isolated from Broiler Farm in Bangladesh

Pathogens, 2020
Multidrug resistant (MDR) Salmonella are a leading cause of foodborne diseases and serious human health concerns worldwide. In this study we detected MDR Salmonella in broiler chicken along with the resistance genes and class 1 integron gene intl1.
Shanzida Binte Alam, Muket Mahmud, Rafiya Akter, Mahadi Hasan, Abdus Sobur, KHM Nazmul Hussain Nazir, Ayman Noreddin, Tanvir Rahman, Mohamed E. El Zowalaty, Marzia Rahman   +9 more
doaj   +1 more source

N‐(1H‐Indazolyl) Aryl Sulfonamide Hybrids as Potential Dihydropteroate Synthase Inhibitors: In Vitro Antibacterial Activity Against Escherichia coli and Staphylococcus aureus and Computational Modeling

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Sixteen indazole–sulfonamide hybrids exhibit species‐dependent antibacterial activity against E. coli and S. aureus, with the lead compound displaying an eightfold lower MIC than sulfathiazole against E. coli. Molecular docking against wild‐type and Sul1‐resistant dihydropteroate synthase identifies a candidate retaining binding affinity toward the ...
Romaisaa Boudza, Ferdaous Elandaloussi, Khalid Boujdi, Jaume Segura‐Garcia, Nabil El Brahmi, Saïd El Kazzouli, Ismaïl Moukadiri, Sergi Maicas, Salim Bounou   +8 more
wiley   +1 more source

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

iLABMED, Volume 4, Issue 3, Page 133-138, September 2026.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

iMetaOmics, Volume 3, Issue 3, September 2026.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos‐Pastén, Gastón Azziz, Rosalba Lagos, Julieta Orlando, Francisco P. Chávez, Andrés E. Marcoleta   +8 more
wiley   +1 more source

Antimicrobial Resistance Pattern and Prevalence of Class 1, 2, and 3 Integrons in Clinical Isolates of Klebsiella Pneumoniae in Loghman-E Hakim Hospital, Tehran

Medical Laboratory Journal, 2015
Background and Objective: Multiple drug resistance has increased in recent years in Klebsiella pneumoniae isolates. The Integrons are mobile genetic elements that carry antibiotics resistance genes.
Derakhshan, S, Najar Peerayeh, SH, Fallah, F, Bakhshi, B   +3 more
doaj  

Molecular analysis of Shiga toxin-producing Escherichia coli O157:H7 and non-O157 strains isolated from calves

Onderstepoort Journal of Veterinary Research, 2018
Shiga toxin-producing Escherichia coli (STEC) O157 and non-O157 are food-borne pathogens and contaminants of foods of animal origin. This study was conducted to investigate the presence of virulence and integrase genes in STEC isolates from diarrhoeic ...
Maryam Kohansal, Ali Ghanbari Asad
doaj   +1 more source