Results 11 to 20 of about 17,399 (221)

[Integrons: gene collectors]. [PDF]

Revista Argentina de microbiologia, 2010
Integrons gained great interest due to their participation in resistance gene recruitment and expression. Their basic structure includes a fragment that encodes an integrase (intI) followed by a recognition sequence (attI) into which they may incorporate gene cassettes (encoding resistance mechanisms). A promoter (Pc) embedded within the integrase gene
J A, Di Conza, G O, Gutkind
openaire   +3 more sources

Resistance integrons: class 1, 2 and 3 integrons [PDF]

Annals of Clinical Microbiology and Antimicrobials, 2015
As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and ...
Deng, Yang, Bao, Xuerui, Ji, Lili, Chen, Lei, Liu, Junyan, Miao, Jian, Chen, Dingqiang, Bian, Huawei, Li, Yanmei, Yu, Guangchao   +9 more
openaire   +2 more sources

Integrons in the development of antimicrobial resistance: critical review and perspectives

Frontiers in Microbiology, 2023
Antibiotic resistance development and pathogen cross-dissemination are both considered essential risks to human health on a worldwide scale. Antimicrobial resistance genes (AMRs) are acquired, expressed, disseminated, and traded mainly through integrons,
Basharat Ahmad Bhat, Rakeeb Ahmad Mir, Hafsa Qadri, Rohan Dhiman, Abdullah Almilaibary, Mustfa Alkhanani, Manzoor Ahmad Mir   +6 more
doaj   +1 more source

Characterization of integrons, extended spectrum beta lactamases and genetic diversity among uropathogenic Escherichia coli isolates from Kerman, south east of Iran

Iranian Journal of Microbiology, 2023
Background and Objectives: The study aimed to investigate the distribution of genes encoding integrons, extended spectrum beta-lactamase (ESBL) in E. coli isolated from UTIs, as well as the genetic diversity among the isolates. Materials and Methods: E.
Samane Mohebi, Zahra Golestani-Hotkani, Maryam Foulad-Pour, Peivand Nazeri, Fahimeh Mohseni, Zahra Hashemizadeh, Zahra Moghani-Bashi, Naser Niksefat, Sanaz Rastegar, Maryam Khajedadian, Zahra Lotfian, Hossein Hosseini-Nave   +11 more
doaj   +1 more source

Into the wild: dissemination of antibiotic resistance determinants via a species recovery program. [PDF]

PLoS ONE, 2013
Management strategies associated with captive breeding of endangered species can establish opportunities for transfer of pathogens and genetic elements between human and animal microbiomes. The class 1 integron is a mobile genetic element associated with
Michelle L Power, Samantha Emery, Michael R Gillings   +2 more
doaj   +1 more source

In Silico Detection of Antimicrobial Resistance Integrons in Salmonella enterica Isolates from Countries of the Andean Community

Antibiotics, 2021
Antimicrobial resistance genes are often associated with integrons, which promote their movement between and within DNA molecules. IntFinder 1.0 and I-VIP v1.2 were used for the detection of integrons and their associated resistance genes in assembled ...
Lilibeth Torres-Elizalde, David Ortega-Paredes, Karen Loaiza, Esteban Fernández-Moreira, Marco Larrea-Álvarez   +4 more
doaj   +1 more source

Gene Expression in Class 2 Integrons Is SOS-Independent and Involves Two Pc Promoters

Frontiers in Microbiology, 2017
Integrons are powerful bacterial genetic elements that permit the expression and dissemination of antibiotic-resistance gene cassettes. They contain a promoter Pc that allows the expression of gene cassettes captured through site-specific recombination ...
Thomas Jové, Sandra Da Re, Aurore Tabesse, Amy Gassama-Sow, Marie-Cécile Ploy   +4 more
doaj   +1 more source

Genomic comparison of diverse Salmonella serovars isolated from swine. [PDF]

, 2019
Food animals act as a reservoir for many foodborne pathogens. Salmonella enterica is one of the leading pathogens that cause food borne illness in a broad host range including animals and humans.
Barrett, John B, Frye, Jonathan G, Gupta, Sushim K, Hiott, Lari M, Humayoun, Shaheen B, Jackson, Charlene R, McClelland, Michael, McMillan, Elizabeth A, Sharma, Poonam, Woodley, Tiffanie   +9 more
core   +2 more sources

Tertiary-Treated Municipal Wastewater is a Significant Point Source of Antibiotic Resistance Genes Into Duluth-Superior Harbor [PDF]

, 2011
In this study, the impact of tertiary-treated municipal wastewater on the quantity of several antibiotic resistance determinants in Duluth-Superior Harbor was investigated by collecting surface water and sediment samples from 13 locations in Duluth ...
Allen H. K., Alonso A., Amann R. I., Andersson D. I., Arthurson V., Auerbach E. A., Benson D. A., Berhardt A. E., Berhardt A. E., Canton R., Cardinale M., Chopra I., Cotner J. B., David T. Tan, Davies J., Diehl D. L., D’Costa V. M., Ghosh S., Graham D. W., Jessica J. Eichmiller, Levy S. B., Levy S. B., Ling L. L., Lipsitch M., Martínez J., Merlin C., Mi Yan, Moura A., Munir M., Nelson D. K., Novo A., Patrick J. McNamara, Pruden A., Ramsden S. J., Sambrook J., Seurinck S., Smith D. L., Sommer M. O. A., Staley J. T., Storteboom H., Tchobanoglous G., Thioulouse J., Thompson J. D., Timothy M. LaPara, Tucker R. Burch, Xi C., Yi L., Zhang T., Zhang X., Zhang X.-X.   +49 more
core   +3 more sources

High prevalence of trimethoprim-resistance cassettes in class 1 and 2 integrons in Senegalese Shigella spp isolates

Journal of Infection in Developing Countries, 2010
Background: Integrons have a well-established role in the dissemination of resistance among Gram-negative pathogens and are thus a useful marker of antibiotic resistance.
Amy Gassama Sow, Awa Aïdara-Kane, Olivier Barraud, Martine Gatet, François Denis, Marie Cécile Ploy   +5 more
doaj   +1 more source