Results 21 to 30 of about 65,623 (263)

Age‐related retinal thickness in Down's syndrome: A high‐risk population for dementia

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019
Introduction People with Down's syndrome (DS) have a high prevalence of early‐onset Alzheimer's disease. Early markers of Alzheimer's disease pathology identifiable before clinical change are needed for the evaluation of preventative treatments.
Madeleine J. Walpert, Eduardo M. Normando, Tiina Annus, Sally R. Jennings, Liam R. Wilson, Peter Watson, Shahid H. Zaman, M. Francesca Cordeiro, Anthony J. Holland   +8 more
doaj   +1 more source

Mapping and identifying service models for community-based services for children with intellectual disabilities and behaviours that challenge in England

BMC Health Services Research, 2023
Background One in five children with an intellectual disability in the UK display behaviours that challenge. Despite associated impacts on the children themselves, their families, and services, little research has been published about how best to design,
Emma L. Taylor, Paul A. Thompson, Nicholas Manktelow, Samantha Flynn, David Gillespie, Jill Bradshaw, Nick Gore, Ashley Liew, Mark Lovell, Kate Sutton, Caroline Richards, Stavros Petrou, Peter E. Langdon, Gemma Grant, Vivien Cooper, Kate Seers, Richard P. Hastings   +16 more
doaj   +1 more source

Synaptopathology Involved in Autism Spectrum Disorder

Frontiers in Cellular Neuroscience, 2018
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental disorders characterized by impaired social communication, social interaction and repetitive behaviors.
Shiqi Guang, Shiqi Guang, Nan Pang, Nan Pang, Xiaolu Deng, Xiaolu Deng, Lifen Yang, Lifen Yang, Fang He, Fang He, Liwen Wu, Liwen Wu, Chen Chen, Chen Chen, Fei Yin, Fei Yin, Jing Peng, Jing Peng   +17 more
doaj   +1 more source

Freeman Center for intellectual and developmental disabilities: Patient-centered interdisciplinary care

Health Care Transitions, 2023
Objectives: Adults with intellectual or developmental disabilities (IDD) face substantial barriers to accessing high-quality, patient-centered care.
Joshua Smith, Brittany N. Hand, Emily Johnson, Corey Keeton, Lauren Wang   +4 more
doaj   +1 more source

Obesity and intellectual disability [PDF]

Mental Retardation and Developmental Disabilities Research Reviews, 2006
AbstractWhile much of the industrialized world struggles for clues to the growing rise in obesity in their respective countries, researchers and service providers involved in understanding the health characteristics and health behaviors of persons with intellectual disability (ID) struggle with their own issues regarding the increased prevalence of ...
James H, Rimmer, Kiyoshi, Yamaki
openaire   +2 more sources

Disruption of mitochondrial and lysosomal functions by human CACNA1C variants expressed in HEK 293 and CHO cells

Frontiers in Molecular Neuroscience, 2023
ObjectiveTo investigate the pathogenesis of three novel de novo CACNA1C variants (p.E411D, p.V622G, and p.A272V) in causing neurodevelopmental disorders and arrhythmia.MethodsSeveral molecular experiments were carried out on transfected human embryonic ...
Miriam Kessi, Miriam Kessi, Miriam Kessi, Baiyu Chen, Baiyu Chen, Baiyu Chen, Langui Pan, Langui Pan, Langui Pan, Li Yang, Li Yang, Li Yang, Lifen Yang, Lifen Yang, Lifen Yang, Jing Peng, Jing Peng, Jing Peng, Fang He, Fang He, Fang He, Fei Yin, Fei Yin, Fei Yin   +23 more
doaj   +1 more source

Intellectual Disability and Parenthood [PDF]

The Scientific World JOURNAL, 2005
Parenthood in persons with intellectual disability (ID) is an issue of concern for the family, guardians, and professionals as there are many sentiments and problems involved: financial, technical, medical, legal, and above all moral. People with intellectual, developmental, or other disabilities have feelings, want relationships, and are able to have ...
Isack Kandel, Mohammed Morad, Gideon Vardi, Joav Merrick   +3 more
openaire   +3 more sources

Comorbid Intellectual Disability [PDF]

Deutsches Ärzteblatt international, 2014
The article by Lehnhardt and colleagues successfully links empirically based facts with the authors' own clinical experiences from a specialized outpatient clinic for people with high-functioning autism; it can therefore be used as a practice guideline for the diagnostic evaluation of adults with suspicion of autism spectrum disorders (1).
Tanja, Sappok, Albert, Diefenbacher, Thomas, Bergmann   +2 more
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The genotype–phenotype correlations of the CACNA1A-related neurodevelopmental disorders: a small case series and literature reviews

Frontiers in Molecular Neuroscience, 2023
BackgroundGenotype–phenotype correlations of the CACNA1A-related neurodevelopmental disorders such as global developmental delay (GDD)/intellectual disability (ID), epileptic encephalopathy (EE), and autism spectrum disorder (ASD) are unknown.
Miriam Kessi, Miriam Kessi, Miriam Kessi, Baiyu Chen, Baiyu Chen, Baiyu Chen, Nan Pang, Nan Pang, Nan Pang, Lifen Yang, Lifen Yang, Lifen Yang, Jing Peng, Jing Peng, Jing Peng, Fang He, Fang He, Fang He, Fei Yin, Fei Yin, Fei Yin   +20 more
doaj   +1 more source

Commentary: The origins of intellectual disability [PDF]

Journal of Child Psychology and Psychiatry, 2022
Despite the importance and prevalence of intellectual disability (ID), its origins have not been well understood until now. Lichtenstein et al. report in this issue findings from a population‐based sample four times larger than all previous family studies of ID put together (Lichtenstein et al., 2022).
openaire   +3 more sources