Results 71 to 80 of about 71,613 (303)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Cahiers des Amériques Latines, 2013 This work shows the findings of a work in progress that characterizes Sandinista intellectuals since 1990; based both on their ideological positions and the nature of their ties with the FSLN.
Héctor Cruz Feliciano +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Private men and public intellectuals: UK historians and changing perceptions of interwar Germany [PDF]
, 2016 UK historians’ work in the interwar era demonstrates their particular significance in shaping the UK’s relationship with Germany. UK interwar historians served in roles that touched upon high politics, and in occupations that gave them unique access to ...
Stenzel, James
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Doutores e Teses em Ciências Sociais
Dados: Revista de Ciências Sociais, 1998 Because the social science narrative has been extremely important in efforts to account for the process of Brazilian modernization, the study of social scientists themselves has become strategic to understanding Brazilian society?s representation of self.
Vianna Luiz Werneck +3 more
doaj
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Black British intellectuals and education : multiculturalism's hidden history
, 2014 While black public intellectuals are an embedded, if often embattled, feature of national life in America, black British thinkers remain routinely marginalised.
Warmington, Paul
core
Intellectuals, Education and Diffusion of Knowledge in Mexico
Ikala: Revista de Lenguaje y Cultura, 2008 This article presents a brief overview of the educational role of intellectuals in the Mexican mass media. The main topics are the diffusion of history and culture, political education, and the propagation of science. This article supports the idea that
Luis Ochoa Bilbao
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source