Results 51 to 60 of about 720,089 (313)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Open source intelligence (OSINT): a contemporary intelligence lifeline [PDF]

open access: yes, 2011
Traditionally, intelligence has been distinguished from all other forms of information working by its secrecy.Secret intelligence is about the acquisition of information from entities that do not wish that information to be acquired and,ideally,never ...
Gibson, S. D.
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Introduction to artificial intelligence techniques for medical image analysis

open access: yes, 2023
As the main goal of artificial intelligence (AI) is to provide inference from a sample, it employs statistics theory to develop mathematical models. When a model is constructed, its description and algorithmic solution for understanding must be competent.
Subasi, Abdulhamit
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Understanding digital intelligence and the norms that might govern it [PDF]

open access: yes, 2015
: This paper describes the nature of digital intelligence and provides context for the material published as a result of the actions of National Security Agency contractor Edward Snowden.
David Omand
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Artificial Intelligence in International Trade: A Bibliometric Analysis [PDF]

open access: yes
Artificial intelligence (AI) has emerged as a key force reshaping the international business landscape. Artificial intelligence, known as one of the disruptive technologies of the moment, will produce important changes in the mechanism of unfolding ...
Mihaela Gabriela Belu
core   +1 more source

An artificial intelligence-based ecological index for prognostic evaluation of colorectal cancer

open access: yesBMC Cancer, 2023
Background and objective In the tumor microenvironment (TME), the dynamic interaction between tumor cells and immune cells plays a critical role in predicting the prognosis of colorectal cancer.
Qicong Chen   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy