Results 41 to 50 of about 1,083,663 (273)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

LOW-PROFILE BI-SLOT DUAL-BAND (2.45/5.76GHZ) ANTENNA FOR WIRELESS COMMUNICATION SYSTEMS

open access: yesJordanian Journal of Computers and Information Technology
This article presents a compact dual-band patch antenna designed for wireless communication systems. The proposed antenna design operates efficiently at both 2.45 GHz and 5.76 GHz achieving high performance despite its compact size.
Ahmed Abbas AL Rimi   +3 more
doaj   +1 more source

The Compatibility of Evolution and Classical Metaphysics

open access: yesStudia Gilsoniana, 2020
The compatibility of evolution with Aristotelian-Thomistic metaphysics is defended in response to Fr. Michal Chaberek’s thesis of incompatibility. The motivation and structure of Darwin’s theory are reviewed, including the roles of secondary causality ...
Dennis F. Polis
doaj   +1 more source

Through the Thicket and Across the Divide:Successfully Navigating the Regulatory Landscape in Life Sciences Research [PDF]

open access: yes, 2013
This chapter addresses the considerable problems that arise within and between regulatory regimes when there is a failure to implement intelligent design that is responsive to the realities of life sciences research.
Harmon, Shawn, Laurie, Graeme
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Unified interest point detection and description for perspective and Fisheye images

open access: yesScientific Reports
Keypoint detection and descriptor matching are essential in tasks like feature matching, object tracking, and 3D reconstruction. While CNN-based methods have advanced these areas, most focus on perspective projection cameras, with limited consideration ...
Jian Xu   +4 more
doaj   +1 more source

An Intelligent Tutoring System for Teaching Grammar English Tenses [PDF]

open access: yes, 2016
The evolution of Intelligent Tutoring System (ITS) is the result of the amount of research in the field of education and artificial intelligence in recent years.
Abu Naser, Samy S.   +2 more
core   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Design of DNA Storage Coding with Enhanced Constraints

open access: yesEntropy, 2022
Traditional storage media have been gradually unable to meet the needs of data storage around the world, and one solution to this problem is DNA storage.
Xiangjun Li, Shihua Zhou, Lewang Zou
doaj   +1 more source

ADO-Tutor: Intelligent Tutoring System for leaning ADO.NET [PDF]

open access: yes, 2017
This paper describes an Intelligent Tutoring System for helping users with ADO.NET called ADO-Tutor. The Intelligent Tutoring System was designed and developed using (ITSB) authoring tool for building intelligent educational systems.
Abu Naser, Samy S.   +1 more
core  

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