Results 61 to 70 of about 44,818 (260)

Impact of Treatment Technique on Testicular Dose and Sexual Activity in Rectal Cancer Patients

open access: yesBrazilian Journal of Oncology
Objective To estimate the incidental radiation dose delivered to the testicles in three-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT), and volumetric-modulated arc therapy (VMAT) in rectal cancer patients ...
Poornachandra Tejaswi-Siddappa   +5 more
doaj   +1 more source

Comparison of simple and complex liver intensity modulated radiotherapy

open access: yesRadiation Oncology, 2010
Background Intensity-modulated radiotherapy (IMRT) may allow improvement in plan quality for treatment of liver cancer, however increasing radiation modulation complexity can lead to increased uncertainties and requirements for quality assurance.
Eccles Cynthia L   +4 more
doaj   +1 more source

Squamous cell carcinoma arising in a sacrococcygeal tailgut cyst [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: We report a case of squamous cell carcinoma originated from a sacrococcygeal tailgut cyst in a 73-year-old female patient. Tailgut cysts are generally multilocal and have a layer of either columnar, squamous or transitional epithelium, or a combination
Arif Hakan Demirel   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Management of Chemotherapy for Stage II Nasopharyngeal Carcinoma in the Intensity-Modulated Radiotherapy Era: A Review

open access: yesCancer Management and Research, 2020
Peng Wu,* Yumei Zhao,* Li Xiang, Linglin Yang Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Linglin ...
Wu P, Zhao Y, Xiang L, Yang L
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Implementation of Aperture-Based Complexity Metrics of MLC Opening based on the IMRT Technique for Central Nervous System (CNS) and Breast cases [PDF]

open access: yesIranian Journal of Medical Physics
Introduction: Complexity metrics have been suggested to characterize treatment plans based on machine parameters such as multileaf collimator (MLC) position.
Meirisa Ambalinggi   +5 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Intensity-modulated radiotherapy (IMRT)

open access: yes, 2007
ill.
Van den Steen, Dirk   +2 more
openaire   +3 more sources

Forward-planned intensity modulated radiation therapy using a cobalt source: A dosimetric study in breast cancer

open access: yesJournal of Medical Physics, 2013
This analysis evaluates the feasibility and dosimetric results of a simplified intensity-modulated radiotherapy (IMRT) treatment using a cobalt-therapy unit for post-operative breast cancer. Fourteen patients were included.
Savino Cilla   +12 more
doaj   +1 more source

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