Results 51 to 60 of about 53,742 (305)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 2017 Purpose: To report outcomes of the rare disease of squamous cell carcinoma (SCC) of the external auditory canal (EAC) and middle ear treated with surgery and postoperative intensity-modulated radiotherapy (IMRT).
陳雅芳;陳婉瑜;許權振;林凱南;郭頌鑫;成佳憲;洪瑞隆;陳育瑄;王成平;蔡巧琳;柯政郁;婁培人 +1 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Journal of the Pakistan Medical AssociationObjective: To compare the efficiency of three-dimensional conformal radiotherapy and intensity-modulated radiation therapy techniques. Method: The cross-sectional study was conducted from February to August 2021 at Al-Amal National Hospital, Baghdad,
Abd Al-Taj Abd Ali Khaleel +4 more
doaj +1 more source
Modern External Beam Radiotherapy Techniques - Intensity Modulated Radiotherapy
, 2009 External beam radiotherapy is a complex cancer radiotherapy technique involving three-dimensional conformal and intensity-modulated radiation therapy high-energy X-ray beam delivery to tumour volumes where dose distributions and treatment plan ...
Śladowska, A.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Chinese Journal of Lung Cancer, 2019 Background and objective The standard treatment for locally advanced non-small cell lung cancer (NSCLC) is radiotherapy concurrent with chemotherapy, but the survival was not satisfied.
Jing YOU +8 more
doaj +1 more source
Three-dimensional conformal radiotherapy versus intensity-modulated radiotherapy in carcinoma cervix
Journal of Clinical and Scientific Research, 2018 Background: Cervical cancer is the most common gynecological cancer among Indian women. 3D-CRT treatment is associated with more acute and late toxicities, because of close proximity of bladder and rectum to the cervix.
Revathi Badiginchala +5 more
doaj +1 more source
Intensity‐modulated radiotherapy for head and neck surgeons [PDF]
Head & Neck, 2015 AbstractThe development of intensity‐modulated radiotherapy (IMRT) has played a major role in improving outcomes and decreasing morbidity in patients with head and neck cancer. This review addresses this vital modality with a focus on the important role of the head and neck surgeon.
Stanley I, Gutiontov +4 more
openaire +2 more sources