Results 41 to 50 of about 1,643,479 (268)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Mesotron Intensity as a Function of Altitude [PDF]
Nature, 1946 DURING July 1945, measurements of the intensity of mesotrons passing through 8 cm. of lead at various heights in the Himalayas up to an altitude of 16,800 ft. were made by me and Mela Ram1. During November 1945, I extended these measurements up to 33,000 ft. above sea-level in an aeroplane flight over Lahore.
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Zanco Journal of Pure and Applied SciencesThe Nonhomogeneous Poisson Process (NHPP), characterized by rate functions that vary over time, is generally used to model the occurrence of events over time.
Parzhin S. Hawez , Khwazbeen S. Fatah
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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IEEE Photonics Journal, 2019 We derive the near-field light intensity distributions of an inorganic LED on its surface and in volumetric space. Our closed-form solution for 3D intensity distribution for a finite-size LED is consistent with Lambert's Cosine Law, which provides
M. Nisa Khan
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On the estimation of poles in intensity functions
Biometrika, 2000 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Choi, E, Hall, Peter
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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