Results 71 to 80 of about 8,064,941 (255)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Discouraging Workers: Estimating the Impacts of Macroeconomic Shocks on the Search Intensity of the Unemployed [PDF]
Discouraged and marginally attached workers have received increased attention from policy makers over the past several years. Theoretically, periods of recessions and high unemployment should directly influence individualÕs decisions whether or not to ...
Stephen B. DeLoach, Mark Kurt
core
On the calculation of plates by the series representation of the deflection function
Қарағанды университетінің хабаршысы. Математика сериясы, 2016 In the article calculations of rectangular plates by the series representation of the deflection function are presented. For the considered rectangular plate the investigation was determined by finding the minimum of the potential energy of the plate by
A.S. Ahanova +2 more
doaj
Effects of High-Intensity Interval Training (HIIT) on Cognitive Function
JKS (Jurnal Kedokteran Syiah Kuala)Introduction: Physical exercise has an important role in the prevention or treatment of cognitive impairment. High Intensity interval training is one of interval training modalities that offers an effective way to improve cognitive function.
Attika Dini Ardiana +1 more
doaj +1 more source
SAGE Open Medicine, 2016 Objectives: Exercise improves endothelial dysfunction, the key manifestation of cardiovascular and cerebrovascular disease, and is recommended in both cardiovascular and cerebrovascular rehabilitation.
Mia Kolmos +2 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Spatial Sound Rendering Using Intensity Impulse Response and Cardioid Masking Function
Applied SciencesThis study presents a new technique for creating spatial sounds based on a convolution processor. The main objective of this research was to propose a new method for generating a set of impulse responses that guarantee a realistic spatial experience ...
Witold Mickiewicz +1 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source