Optically guided intensity modulated radiotherapy
Previously, we reported on development of an optically guided system for 3D conformal intracranial radiotherapy using multiple noncoplanar fixed fields. In this paper we report on the extension of our system for stereotactic fractionated radiotherapy to include intensity modulated static ports.A 3D treatment plan with maximum beam separation is ...
Department of Human Oncology, University of Wisconsin, K4/B100 Clinical Science Center Highland Avenue, Madison, WI 53792 USA ( host institution ) +7 more
openaire +3 more sources
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Intensity modulation and direct detection quantum key distribution based on quantum noise
Quantum key distribution (QKD) has been studied for achieving perfectly secure cryptography based on quantum mechanics. This paper presents a novel QKD scheme that is based on an intensity-modulation and direct-detection system.
Takuya Ikuta, Kyo Inoue
doaj +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The performance of intensity modulation (IM) with direct detection (DD) transmission systems is enhanced through a novel combination of multidimensional coding, Nyquist pulse shaping, and electronic dispersion compensation (EDC) at the transmitter using ...
Julien Moussa H. Barakat +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Longitudinal piezoelectric resonant photoelastic modulator for efficient intensity modulation at megahertz frequencies. [PDF]
Atalar O +3 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Analyzing Peak-to-Average Power Ratio Characteristics in Multi-Channel Intensity Modulation and Direct Detection Flexible Transceivers Deploying Inverse Fast Fourier Transform/Fast Fourier Transform-Based Processing. [PDF]
Chen L +7 more
europepmc +1 more source
Adaptive modulation schemes for optical wireless communication systems [PDF]
High-speed wireless optical communication links have become more popular for personal mobile applications. This is a consequence of the increasing demand from the personal information service boom.
Zeng, Yu
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