Results 121 to 130 of about 2,307,247 (300)

Outcome of Adenoid Cystic Carcinoma of Head and Neck After Postoperative Intensity Modulation Radiotherapy: A Single Institution Study. [PDF]

Cancer Manag Res, 2021
Xu P, Wang S, Luo Y, Yin J, Belkacemi Y, Lu S, Feng M, Lang J.   +7 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Time Span of an Image Frame Using a CMOS Sensor in Rolling Shutter‐Based Optical Camera Communications

IET Optoelectronics
In this paper, a rolling shutter optical camera communication system is investigated by analysing the internal working principle of a receiver based on complementary metal oxide semiconductor image sensors.
Raul Zamorano‐Illanes, Zabih Ghassemlooy, Xicong Li, Othman Younus, Stanislav Zvánovec, Ismael Soto   +5 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Fundamental Physics at the Intensity Frontier

, 2011
This workshop is an opportunity for the scientific community to identify the physics potential of the Intensity Frontier. Starting in September 2011, six working groups will study and begin to document the full spectrum of opportunities for fundamental ...
Intensity Frontier Workshop
core   +1 more source

Anomalous hot electron generation from two-plasmon decay instability driven by broadband laser pulses with intensity modulations

Nuclear Fusion
We investigate the hot electrons generated from two-plasmon decay (TPD) instability driven by laser pulses with intensity modulated by a frequency Δ ω _m using theoretical and numerical approaches.
C. Yao, J. Li, L. Hao, R. Yan, C. Wang, A. Lei, Y-K. Ding, J. Zheng   +7 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Intensity modulation of UV light in gas sensor array to discriminate several analytes at room temperature

IET Science, Measurement & Technology
In this study, a gas sensor array along with intensity modulation of UV light was utilized to discriminate several gases at room temperature. The sensor array was consisted of two interdigitated microelectrodes and TiO2 nanofibres were electrospun on ...
Ahmad Reza Sadredini, Alireza Nikfarjam, Mohsen Naeimi Pour, Niloofar Nazeri   +3 more
doaj   +1 more source