Results 131 to 140 of about 3,670,840 (396)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 2007 Based on silicon-on-insulator (SOI) technology, a Mach-Zehnder interferometer (MZI) is fabricated, in which two directional couplers serve as power splitter and combiner.
Yu JZ (Yu Jinzhong) +3 more
core
Intensity modulation of a hybrid integrated diode laser [PDF]
, 2022 Hybrid integrated diode lasers are compact, widely tunable and can be designed to have extremely low intrinsic line width. Here we investigate the intensity modulation response of a such a laser having a tuning range of 100 nm around 1550 nm. Utilizing a
van Rees, Albert; id_orcid +3 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
IEEE Photonics JournalThe performance of intensity modulation (IM) with direct detection (DD) transmission systems is enhanced through a novel combination of multidimensional coding, Nyquist pulse shaping, and electronic dispersion compensation (EDC) at the transmitter using ...
Julien Moussa H. Barakat +4 more
doaj +1 more source
Longitudinal piezoelectric resonant photoelastic modulator for efficient intensity modulation at megahertz frequencies. [PDF]
Nat Commun, 2022 Atalar O +3 more
europepmc +1 more source
DC-informative subcarrier intensity modulation for visible light communication [PDF]
, 2017 25th Signal Processing and Communications Applications Conference (SIU) -- MAY 15-18, 2017 -- Antalya, TURKEYWOS: 000413813100200In this paper, the performance of direct current informative subcarrier intensity modulation (DCI-SIM) which is proposed to ...
Çelik, Yasin +4 more
core +1 more source
Fiber-optic microphone based on combination of Fabry–Perot interferometry and intensity modulation [PDF]
, 1995 Chonghua Zhou +2 more
openalex +1 more source
Optically guided intensity modulated radiotherapy
Radiotherapy and Oncology, 2001 Previously, we reported on development of an optically guided system for 3D conformal intracranial radiotherapy using multiple noncoplanar fixed fields. In this paper we report on the extension of our system for stereotactic fractionated radiotherapy to include intensity modulated static ports.A 3D treatment plan with maximum beam separation is ...
Department of Human Oncology, University of Wisconsin, K4/B100 Clinical Science Center Highland Avenue, Madison, WI 53792 USA ( host institution ) +7 more
openaire +3 more sources
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source