Results 171 to 180 of about 2,307,247 (300)

Suitable Combination of Direct Intensity Modulation and Spreading Sequence for LIDAR with Pulse Coding. [PDF]

Sensors (Basel), 2018
Kim G, Park Y.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Defining the role of intensity modulation in electron conformal therapy for the treatment of head and neck cancer. [PDF]

Med Dosim
Cabrera J, Erhart K, Kelly P, Zeidan OA, Swanick C, Rineer J, Shah AP.   +6 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Toward Complete All-Optical Intensity Modulation of High-Harmonic Generation from Solids. [PDF]

ACS Photonics
van Essen PJ, Nie Z, de Keijzer B, Kraus PM.   +3 more
europepmc   +1 more source

Dose optimization strategy of sacrum limitation in cervical cancer intensity modulation radiation therapy planning. [PDF]

Medicine (Baltimore), 2019
Guo Q, Cai S, Qian J, Tian Y.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Does intensity modulation increase target dose calculation errors of conventional algorithms for lung SBRT? [PDF]

J Appl Clin Med Phys, 2018
Zheng D, Verma V, Wang S, Liang X, Zhou S.   +4 more
europepmc   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Metadevice for intensity modulation with sub-wavelength spatial resolution. [PDF]

Sci Rep, 2016
Cencillo-Abad P, Zheludev NI, Plum E.
europepmc   +1 more source